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68 -- EasySep Human Immune Cells Enrichment kits

Notice Date
6/29/2020 4:14:37 PM
Notice Type
Sources Sought
325414 — Biological Product (except Diagnostic) Manufacturing
Contracting Office
ZIP Code
Solicitation Number
Response Due
7/13/2020 8:00:00 AM
Archive Date
Point of Contact
Fred Ettehadieh
E-Mail Address
Description:� This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.� It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.� Responses will not be considered as proposals or quotes.� No award will be made as a result of this notice.� The Government will NOT be responsible for any costs incurred by the respondents to this notice.� This notice is strictly for research and information purposes only. Background:� The central hypothesis of our ongoing project (GESTALT) is that immune dysfunction contributes directly to chronic inflammation and inflammation-associated diseases in the elderly. To understand the basis for immuneimpairment that accompanies aging, we proposed to identify age-associated alterations in human innate and adaptive immune cell populations. Cytapheresis packs are collected from volunteers of varying age-groups and the different immune na�ve or total cells (B, CD4+T and CD8+T) are fractionated by the EasySep Human isolation kits using the RoboSep cell isolation instruments. The ongoing project is to examine age-associated changes in transcriptomes, proteomes and epigenomes of these immune cell subsets that obtained from these GESTALT participants. � Purpose and Objectives: �The purpose of this request is to purchase the EasySep Human total and Na�ve B, CD4+ T and CD8+ T isolation kits, and total monocyte kits. These kits are used to fractionate the different mentioned specific cells from the GESTALT PBMC samples. Project requirements: EasySep Human Na�ve B cell isolation kit (cat. # 17254), EasySep Human Na�ve CD4+ T iolation Kit II (cat. # 17555) and EasySep Human Na�ve CD8+ T isolation kit II (cat. # 17968), EasySep Human CD3 Pos Sel kit II (cat. # 17851), EasySep Human Monocyte Enrichment kit (cat. # 19058), EasySep Negative Human CD4 kit (cat. # 19052), EasySep Negative Hman CD8 (cat. # 19053), EasySep Negative Human B cell (cat. # 19054), ImmunoCult-SF Macrophage Medium (cat. 10961), ImmunoCult-XF Tcell Medium (cat. # 10981), ImmunoCult Hu CD3/CD28 (cat. #10991), Robosep Buffer (cat. # 20104) and Robosep Filter Tip Racks (cat. # 20125). Delivery Schedule:� 2-3 deliveries starting 30 days after award. Salient characteristics: General a.�������� Fast and Easy: isolated cells are immediately ready for use. b.�������� Efficient: perform sequential or simultaneous cell isolations. c.�������� Safe: with column-free design and minimal sample handling required, the risk of �� ����������� exposure to dangerous pathogens is minimized. d.�������� Free from cross-contamination: disposable tips and a column free system ����������� eliminate the risk of sample cross-contamination. Capability statement /information sought. Respondents must provide, as part of their responses, a capability statement that includes information regarding respondents�: (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information. The respondent must also provide their� DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2� x 11� paper size, with 1� top, bottom, left and right margins, and with single or double spacing. The information submitted must be in an outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein.� A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit.� The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents� technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer.� Facsimile responses are NOT accepted. The response must be submitted to Fred Ettehadieh, Contracting Officer, at e-mail address fred.ettehadieh@nih.gov. � The response must be received on or before July 13, 2020 at 11:00 AM, Eastern Time. �Disclaimer and Important Notes:� This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).�
Web Link
SAM.gov Permalink
Place of Performance
Address: Baltimore, MD, USA
Country: USA
SN05707001-F 20200701/200629230159 (samdaily.us)
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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