Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF JULY 30, 2020 SAM #6818
SOLICITATION NOTICE

66 -- FDA - Notice of Intent to Sole Source Nanostring Cassettes and Reagents - 1228458

Notice Date

7/28/2020 12:24:46 PM
 

Notice Type

Presolicitation
 

NAICS

541713 — Research and Development in Nanotechnology
 

Contracting Office

FDA Office of Acquisitions and Grants Services Rockville MD 20857 USA
 

ZIP Code

20857
 

Solicitation Number

1228458
 

Response Due

8/4/2020 12:00:00 PM
 

Archive Date

08/04/2020
 

Point of Contact

Maeve Xavier, Phone: 2404027609
 

E-Mail Address

Maeve.Xavier@fda.hhs.gov
(Maeve.Xavier@fda.hhs.gov)
 

Description

In accordance with FAR 13.501(a)(1)(ii),�Only one responsible source and no other supplies or services will satisfy agency requirements. The FDA requires�the purchase and delivery of Nanostring cassettes and reagents. The project for which this contract is being issued supports a research program to evaluate the usefulness of humanized mice (HM) for regulatory purposes. The HM are created by surgical implantation of human tissue into mice that have multiple genetic mutations that block the development of the mouse immune system at a very early stage. To complete the immunogenicity studies with these humanized mice, we are evaluating the usefulness of a technology to assess the gene expression of over 500 genes simultaneously from one sample, with multiple samples processed at the same time. Nanostring cassettes provide the ability to assay over 500 genes� expression simultaneously for a single sample. There are twelve sample wells in each cassette allowing multiple samples to be assessed at the same time. This technology provides a high sensitivity, high-throughput technique to assess gene expression that would otherwise require significantly greater investment of time and money to obtain the same information via more conventional assays. CDER is currently using the nCounter� MAX Analysis System, which is proprietary to Nanostring Technologies. The cassettes used in this system are unique to Nanostring Technologies and are not manufactured or distributed by other vendors. In addition, all validation and development work has already been completed using the nCounter� MAX Analysis System.
 

Web Link

SAM.gov Permalink
(https://beta.sam.gov/opp/9970f83f77e742d3baa972fd4666e02f/view)
 

Place of Performance

Address: Silver Spring, MD 20993, USA

Zip Code: 20993

Country: USA
 

Record

SN05736574-F 20200730/200728230143 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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