Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF AUGUST 09, 2020 SAM #6828
SOLICITATION NOTICE

Q -- Gene synthesis, site-directed mutagenesis and plasmid prep

Notice Date

8/7/2020 2:45:26 PM
 

Notice Type

Presolicitation
 

NAICS

541990 — All Other Professional, Scientific, and Technical Services
 

Contracting Office

NATIONAL INSTITUTES OF HEALTH NIAID BETHESDA MD 20892 USA
 

ZIP Code

20892
 

Solicitation Number

NOI-NIAID-2028966
 

Response Due

8/17/2020 7:00:00 AM
 

Archive Date

09/01/2020
 

Point of Contact

Skye Duffner, Phone: 4068026092, Julienne Keiser, Phone: 4063639370
 

E-Mail Address

skye.duffner@nih.gov, jkeiser@niaid.nih.gov
(skye.duffner@nih.gov, jkeiser@niaid.nih.gov)
 

Description

This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with GeneImmune Biotechnology, Rockville, MD 20855 for site-directed mutagenesis, gene synthesis, and plasmid prep. The mission of the NIH Vaccine Research Center (VRC) is to facilitate the development of vaccines against HIV-AIDS. Our goal is to develop immunogens that will elicit broadly neutralizing antibodies and will be used in vaccine design. One of the aims of the project is to obtain atomic level structures of the envelope glycoproteins that are the sole exterior target for neutralizing antibodies. Another aim is to develop neutralizing antibodies against HIV. In order to reach our goal, a large variety of proteins need to be made. We make the proteins from the site-directed muta-genesis, plasmid prep and gene synthesis that Gene Universal service provides. This is a sole-source because GeneImmune Biotechnology has base DNA that is in use for this project and synthesizes and sequences from the base DNA samples they have. Any other source of services will require extensive retesting and delay our production of materials for vaccine development and clinical trials for this project. No substitutions are accepted for this project. The statutory authority for this sole source requirement is 41 U.S.C.1901 (e) (2) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide comparable services may submit a capability statement that will be considered by email (subject line to reference NOI-NIAID-2028966) to Skye Duffner at skye.duffner@nih.gov, by 10:00 am eastern standard time, August 17, 2020. All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government
 

Web Link

SAM.gov Permalink
(https://beta.sam.gov/opp/6dad8517e8b646488099679a1271e3d9/view)
 

Place of Performance

Address: Bethesda, MD 20892, USA

Zip Code: 20892

Country: USA
 

Record

SN05749283-F 20200809/200807230139 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

---

| FSG Index  |  This Issue's Index  |  Today's SAM Daily Index Page |