AWARD
99 -- Effect of Psychological and Medication Treatments on Physiological Response to Unpredictable Threat
- Notice Date
- 1/5/2021 2:38:11 PM
- Notice Type
- Award Notice
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 21-000025
- Archive Date
- 01/19/2021
- Award Number
- 75N95021P00060
- Award Date
- 12/29/2020
- Awardee
- GEORGETOWN UNIVERSITY (THE) Washington DC USA
- Award Amount
- 36000.00
- Description
- Fixed-Priced, Non-Competitive� Description of Service: This study is a collaboration between the Section on the Neurobiology of Fear and Anxiety (SNFA) at the NIMH and Georgetown University Medical Center (GUMC). SFNA studies the pathophysiology of anxiety disorders to improve treatment for these conditions. GUMC conducts trials, for example, to compare the effectiveness of two treatments for anxiety disorders, escitalopram and Mindfulness-Based Stress Reduction. The objective of the collaboration was to add a research component to clinical trials conducted with anxiety patients. Specifically, SNFA is �seeking to identify biomarkers of treatment response. Patients with anxiety disorders who enroll in a GUMC treatment study also have the option to participate in a psychophysiological investigation that examines their physiological and subjective reactivity to threat. Both the clinical trials and the psychophysiological study are conducted at GUMC. GUMC was not funded to implement the psychophysiological study, which was designed by SNFA. This study continues to assist our ability to better associate an individual with efficient treatment. Justification Rationale: The study �examines how psychological (e.g., mindfulness) and medication (e.g., selective serotoninergic reuptake inhibitor) treatments affect psychophysiological responses to threat in patients with anxiety disorders. The contractor is required to have access to a large number of patients with anxiety disorders and to enroll these patients in treatment studies. The contractor also needs to have equipment to conduct the psychophysiological experiment. This is currently the third year of an ongoing study between between SNFA and the GUMC, and, all the data accumulated in the first two years will not be useful if the study does not completed. The protocol requires testing the patients twice and changing vendors during the middle of a protocol will compromise the data. Since many of the patients have already been tested once (before treatment) and will require another test (after treatment), the same vendor is required to provide the second test per our protocol. The additional patients that will be enrolled need to be tested with the same methodolog as previous patients. This contract is necessary to complete the study after already completing two years of testing. In the scientific world, one can not simply change vendors in the middle of a protocol. The results would simply be compromised.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/d4e3d878d89c45eab0ca6353955a90ca/view)
- Record
- SN05884681-F 20210107/210105230108 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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