SOURCES SOUGHT
99 -- �In Vitro Assessment for Antimicrobial Activity Against SARS-CoV-2�
- Notice Date
- 1/14/2021 1:18:58 PM
- Notice Type
- Sources Sought
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIAID BETHESDA MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 75N93020Q00001
- Response Due
- 1/20/2021 2:00:00 PM
- Archive Date
- 02/04/2021
- Point of Contact
- Alexandra Buck, Phone: 2406695174, Brian Madgey, Phone: 2406273712
- E-Mail Address
-
alexandra.buck@nih.gov, madgeyba@mail.nih.gov
(alexandra.buck@nih.gov, madgeyba@mail.nih.gov)
- Description
- The NIAID intends to solicit proposals for the performance of approximately two hundred (200) assessments of test molecules.� Each assessment shall evaluate and verify viral inhibitory activity of test molecules against authentic SARS-CoV-2 in human cells as well as provide an assessment of cytotoxicity.� Each assessment shall be completed within fourteen (14) calendar days of receipt of the test molecule.� For each test molecule at least 8 concentrations shall be evaluated to allow for the generation of a dose-response curve to generate EC50 and EC90 values (as possible).� In addition, the contractor shall determine the in vitro cytotoxicity and use this to calculate the CC50. Finally, the contractor shall calculate a selectivity index (SI) based on the EC50 and CC50 values.� Each evaluation shall include a positive control to validate and measure assay performance and accuracy. The duration of the firm fixed price purchase order is twelve months.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/b7f78b6def5244ac961268a6959e6eff/view)
- Record
- SN05892949-F 20210116/210114230112 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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