SOLICITATION NOTICE
R -- Long-read sequencing to detect genomic and epigenetic features of Alzheimer�s Disease and Related Dementias
- Notice Date
- 4/13/2021 4:38:22 AM
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 75N95021Q00105
- Response Due
- 4/20/2021 12:00:00 PM
- Archive Date
- 05/05/2021
- Point of Contact
- Scott Bredow, Phone: 3014807503
- E-Mail Address
-
scott.bredow@nih.gov
(scott.bredow@nih.gov)
- Description
- NIH/CARD will generate long-read sequencing data from roughly 4000 patients with Alzheimer�s disease (AD), frontotemporal dementia (FTD), Lewy body dementia (LBD), and healthy subjects. This project will produce roughly 8000 terabytes of data, so the government will need a Contractor to develop pipelines for storing, analyzing, and harmonizing these large data sets on cloud-based computing platforms. The Contractor shall then use these datasets to identify DNA methylation changes and single nucleotide variants, both of which have been linked to normal aging and neurodegenerative diseases. The government will then use this service provided by the Contractor to evaluate how the epigenetic and genomic landscape in challenging regions contribute to the development of neurodegenerative diseases.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/6cdd66fd13184905ac0ba83dca7f3d0d/view)
- Record
- SN05970558-F 20210415/210413230113 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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