SPECIAL NOTICE
F -- GRAY WHALE EPIGENETICS USING DArTseq-Met METHOD FOR NOAA SOUTHWEST FISHERIES SCIENCE CENTER IN LA JOLLA, CA
- Notice Date
- 6/2/2021 6:15:02 AM
- Notice Type
- Special Notice
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION US
- ZIP Code
- 00000
- Solicitation Number
- NFFR7200-21-02441MCW
- Response Due
- 6/17/2021 1:00:00 PM
- Archive Date
- 07/02/2021
- Point of Contact
- Michelle C Walton, Phone: 3034976335
- E-Mail Address
-
Michelle.Walton@noaa.gov
(Michelle.Walton@noaa.gov)
- Description
- ***NOAA'S ACQUISITION & GRANTS OFFICE, WESTERN ACQUISITION DIVISION-BOULDER, NATIONAL MARINE FISHERIES SERVICE (NMFS), SOUTHWEST FISHERIES SCIENCE CENTER (SWFSC) INTENDS TO NEGOTIATE, ON A SOLE SOURCE BASIS, UNDER AUTHORITY OF FAR 13.106-1(b)(1), WITH DIVERSITY ARRAYS TECHNOLOGY PTY LIMITED OUT OF AUSTRALIA FOR DARTSEQ-MET ANALYSIS OF GRAY WHALES. ***THE SOLE SOURCE DETERMINATION IS BASED ON THE NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION'S (NOAA) REQUIREMENT THAT DIVERSITY ARRAYS TECHNOLOGY IS THE ORIGINAL DEVELOPER OF THE DARTSEQ METHOD TO GENERATE EPIGENETIC DATA. DIVERSITY ARRAYS IS THE ONLY VENDOR THAT CAN PROVIDE THE SERVICES NEEDED TO COMPLETE ALL STAGES OF THIS WORK. OTHER APPROACHES NECESSITATE THAT A �PLATINUM QUALITY� REFERENCE GENOME IS AVAILABLE, WHICH IS CURRENTLY NOT AVAILABLE FOR GRAY WHALES. IN ADDITION, WHILE OTHER TECHNOLOGIES HAVE BEEN DEVELOPED WHICH UTILIZE A SINGLE RESTRICTION ENZYME TO SELECT FRAGMENTS OF THE GENOME, THE TECHNOLOGY DEVELOPED BY DIVERSITY ARRAYS (DARTSEQ-MET) INCORPORATES THE USE OF PAIRED ENZYMES (I.E., A DOUBLE DIGESTION) ALLOWING FOR GREATER SELECTIVITY OF FRAGMENTS, INCREASED SCALABILITY AND HIGH REPRODUCIBILITY OF THE FRAGMENTS SEQUENCED. THIS IS NECESSARY TO ALLOW COST-EFFECTIVE ANALYSIS OF OVER 200 SAMPLES AT SUFFICIENT SEQUENCING DEPTH FOR RELIABLE ANALYSIS. THE DARTSEQ-MET APPROACH PRODUCES TWO PARALLEL LIBRARIES FOR EACH SAMPLE, WHERE THE ENZYME PAIR USED TO PRODUCE ONE LIBRARY INCLUDES A METHYLATION SENSITIVE ENZYME WHILE THE OTHER DOES NOT. CONTRASTING THE DATA PRODUCED IN THE TWO LIBRARIES ALLOWS FOR THE RELIABLE DETECTION OF THOUSANDS OF METHYLATED VERSUS NON-METHYLATED SITES. THE PRODUCTION OF DUAL LIBRARIES PER SAMPLE ELIMINATES THE NEED TO RUN A CONTROL SAMPLE, WHICH IS NECESSARY IN OTHER METHODS (E.G., MSAP-SEQ). DIVERSITY ARRAYS TECHNOLOGY OWNS A PATENT FAMILY COVERING DART TECHNOLOGY BASED ON US PATENT NO 6,713,258 B2. ***THIS NOTICE OF INTENT IS NOT A REQUEST FOR COMPETITIVE PROPOSALS AND NO SOLICITATION PACKAGE IS AVAILABLE. HOWEVER, FIRMS THAT BELIEVE THEY CAN FULLY MEET THE GOVERNMENT'S REQUIREMENTS MAY SUBMIT SUBSTANTIATING DOCUMENTATION IN WRITING TO THE IDENTIFIED POINT OF CONTACT WITHIN 15 DAYS AFTER PUBLICATION OF THIS SYNOPSIS. SUCH DOCUMENTATION WILL BE EVALUATED SOLELY FOR THE PURPOSE OF DETERMINING WHETHER OR NOT TO CONDUCT THIS PROCUREMENT ON A COMPETITIVE BASIS. A DETERMINATION BY THE GOVERNMENT NOT TO CONDUCT A COMPETITIVE PROCUREMENT, BASED UPON RESPONSES TO THIS NOTICE, IS SOLELY WITHIN THE DISCRETION OF THE GOVERNMENT. ORAL COMMUNICATIONS ARE NOT ACCEPTABLE IN RESPONSE TO THIS NOTICE.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/41bceb1a2a2a4c1d937f1d091d2d0e3e/view)
- Place of Performance
- Address: AUS
- Country: AUS
- Country: AUS
- Record
- SN06018724-F 20210604/210602230116 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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