SOURCES SOUGHT
66 -- Acquisition of a JPK NanoWizard� 4 XP Nano Science Atomic Force Microscope (AFM) System
- Notice Date
- 6/6/2021 5:30:25 PM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NICHD BETHESDA MD 20817 USA
- ZIP Code
- 20817
- Solicitation Number
- NICHD-21-138
- Response Due
- 6/11/2021 6:00:00 AM
- Archive Date
- 06/26/2021
- Point of Contact
- Amber Harris, Fax: 3014803278
- E-Mail Address
-
amber.harris@nih.gov
(amber.harris@nih.gov)
- Description
- SOURCES SOUGHT NOTICE (Acquisition of a JPK NanoWizard� 4 XP Nano Science Atomic Force Microscope (AFM) System) AGENCY: �The National Institutes of Health, National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) TITLE: Acquisition of a JPK NanoWizard� 4 XP Nano Science Atomic Force Microscope (AFM) System PROPOSED SOLICITATION NUMBER: NICHD-21-138 PROJECT SERVICE CODE: 6640 - LABORATORY EQUIPMENT AND SUPPLIES This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. There is no solicitation available at this time. The purpose of this notice is to obtain information regarding: (1) the availability and capability of all qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification according to the North American Industry Classification System, (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set- aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. BACKGROUND: The mission of the National Institutes of Health (NIH) is to seek fundamental knowledge about the nature and behavior of living systems and to apply that knowledge to enhance health, lengthen life, and reduce illness and disability. � As part of the NIH, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Intramural Research Program (IRP) conducts biomedical research and training related to diabetes mellitus; endocrine, bone, and metabolic diseases; digestive diseases, including liver diseases and nutritional disorders; and kidney, urologic, and hematologic diseases. Intramural research is conducted in the Institute's laboratories and clinical facilities in Bethesda, Maryland and in Phoenix, Arizona. � Miroshnikova lab and the Section on Nuclear Mechanotransduction and Cell Fate Dynamics is part of Laboratory of Molecular Biology (LMB), which is one of NIDDK IRP 17 Laboratories and Branches. �Miroshnikova lab�s work requires, on an ongoing basis, advanced mechanical characterization methods to qualitatively complement other assays, as well as quantitate the major experimental conditions of the section in living cells and organisms. JPK�s atomic force microscope is leading, high-resolution system combing atomic resolution and fast scanning with rates of up to 150 lines/sec and a large scan range of 100�m in one system allowing cell-cell force quantification in addition to mechanical properties of cells, organelles and tissues. It is designed to provide highest mechanical and thermal stability on inverted optical microscopes during long term experiments on samples ranging from single molecules to living cells and tissues. Thus, it is ideal for live cell and tissue/organism imaging and quantitation, which is at the core of Miroshnikova lab operations. The objective of this requirement is to purchase a new live-sample microscope system with DirectOverlay� 2 software compatibility for perfect integration and data correlation with advanced fluorescence microscopy platforms; meaning that the system must allow calibration of optical images and precisely overlay both the optical and the AFM images. This system must conduct mechanical characterization and cell-cell adhesion measurements due to 100micron z scan size, as well as side visualization of the sample. SALIENT / REQUIRED FEATURES AND SPECIFICATIONS: The new equipment must include the below features necessary to satisfy day to day Miroshnikova lab operations. Atomic Force Microscope (AFM) System AFM Head� ��� �Multi-purpose stand-alone tip-scanning design� ��� �Closed-loop atomic lattice resolution (mica in buffered solution) on inverted microscope under suitable environmental conditions� ��� �Drift minimized concentric design� ��� �Available sample size �140mm x18mm; unlimited for large samples due to tip-scanning design� ��� �Head completely sealed against vapor and liquids� ��� �High Resolution Mode (HRM) delivers atomic resolution (mica lattice in air or buffered solution) on inverted microscope under suitable environmental conditions (active vibration isolation and acoustic enclosure)� ��� �Lowest cantilever deflection noise of any commercial AFM (20mm x 20 mm� ��� �Step size (Resolution): ?1 ?m� ��� �Repeatability (unidirectional): ?2 ?m� ��� �Maximum velocity: 1mm/s� ��� �Compatible with all JPK sample carriers e.g., for glass slides, Petri dishes, �� �coverslips, metal discs, etc.� ��� �Please specify the microscope model when ordering� Fluid Cells and Temperature Control ��� �Insert for Life Science stage� ��� �Temperature range: Room temperature up to 60�� ��� �Compatible with 35x10mm Petri dishes from WPI and TPP (plastic or plastic with �� �glass bottom)� ��� �Adaptors for other suppliers such as Matek, Willco, IWAKI, Ibidi, and BC upon �� �request� ��� �Ports for perfusion tubes and gas supply (only available for certain types of Petri �� �dishes)� ��� �Silicone anti-evaporation seal� ��� �Software control� ��� �Temperature stability 0.1 K� ��� �Please specify the inverted microscope model when ordering� Systems and Configurations for all systems� JPK TopView Optical module to view tip and sample ��� �Integrated camera with images captured directly into the AFM software� ��� �Can be mounted on the AFM head while the head is mounted on the inverted �� �fluorescence microscope as well as standalone� ��� �Top down view perpendicular to sample plane� ��� �Magnification 10x� ��� �Up to 5MP, frame rate max 9 FPS� ��� �Camera connection type USB 2.0� ��� �Please specify the Head (H-XX-XX) JPK SideView� cantilever holder - Side View ��� �Super cut, fixed spring, length: 15.5 mm� ��� �Cantilever holder with precise mounted mirror� ��� �Allows both view from below and front of cantilever� ��� �Visual observation of tip-sample region e.g. for cell pick-up� ��� �Compatible with aqueous solutions and epi-illumination� ��� �Available numerical aperture: 0.3 *Objectives with minimum 4mm working distance required (20x recommended). Sideview and Hybrid stage Nikon are compatible.� Microscopy Kits� JPK Optical System Data Communication Kit ��� �Ubuntu file transfer between JPK SPM and another optical image system for data �� �transfer for DirectOverlay�� ��� �With hardware (network switch, network cables and TTL-cable with BNC �� �connection)� c-mount 1.0x camera adapter SlimFocus objective lens z-Scanner ��� �SlimFocus z tracking with position sensor for microscope objectives� ��� �Digital controller� ��� �1.5m cable� ��� �Objective lens adapter� ��� �SlimFocus z tracking software� ��� �Range (open loop/closed loop): 180?m/150?m� ��� �Resolution (open loop/closed loop): 1.5nm� ��� �2 BNC cable 2 m length� Vibration and Acoustic Isolation� Benchtop Active Vibration Isolation System� ��� �Approved for use with JPK NanoWizard� AFM� ��� �Active bandwidth 0.6 Hz � 200 Hz� ��� �Isolation: 40 dB above10 Hz� ��� �Dimensions: 400 x 500 x 85 mm�� ��� �Weight: 20kg� ��� �External power supply Independently, and not as an agent of the Government, the contractor shall provide equipment and delivery services for Miroshnikova Lab Specifically, the NIDDK requires completion of the following tasks: Task Area 1 � Delivery shall be within 3 months from when Purchase Order was sent to the vendor. Task Area 2 � Shipping will be provided by the vendor to Building 5, Rm 316I, 9000 Rockville Pike, Maryland 20892, which is Miroshnikova�s lab microscopy space.� Task Area 3 � Installation will be provided by factory-trained service engineers of the manufacturer, no later than 2 weeks after delivery, unless postponed by request of the government. Task Area 4 � Warranty will be provided by the manufacturer and serviced by their local service engineer(s) will be no less than 1 year from completion of installation, covering all deliverables, labor, labor and travel, minus consumables. Task Area 5 � Training will be provided within 1 week after installation by applications specialist(s) from the manufacturer.. This Sources Sought is for an organization or institution to provide the NIDDK with JPK NanoWizard� 4 XP Nano Science Atomic Force Microscope (AFM) System. �The purchase of this instrument is necessary to maintain the high quality of our research. � All qualified small businesses, whether they are small businesses; HUBZone small businesses; service-disabled, veteran owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; interested in submitting a corporate capability statement should demonstrate their capability to provide equipment that meets the characteristics above. SPECIAL INSTRUCTIONS: This acquisition is being conducted under the authority of FAR Part 13.5 Simplified Acquisition Procedures. This is a competitive requirement conducted under the authority of FAR 52.211-6, Brand Name or Equal. �This is a requirement for BRUKER NANO, INC. JPK NanoWizard� 4 XP Nano Science Atomic Force Microscope (AFM) System. � The vendor will be evaluated on their quoted product meeting the specifications under section SALIENT / REQUIRED FEATURES AND SPECIFICATIONS. If you or your firm/business has an interest and possess the required expertise we invite you to submit a corporate capability statement to assist the Government in determining in accordance with Federal Acquisition Regulation (FAR) 19.502-2(b) whether or not this procurement will be set-aside for any of the programs described above. The associated NAICS code is 334516, Analytical Laboratory Instrument Manufacturing, and the small business size standard is 1,000. �All respondents are requested to identify their firm's size and type of business. Interested firms responding to this Sources Sought Notice should adhere to the following: (a) Provide a capability statement demonstrating relevant experience, skills and ability to fulfill the Government's requirements for the above. The capability statement should contain sufficient detail for the Government to make an informed decision regarding your capabilities. The capability statement should not exceed 15 pages using a font size 10 or larger. (b) Small business concerns that possess the capabilities necessary to undertake the efforts should submit complete documentation of their capabilities to the Contracting Officer. This capability statement should include: 1) the total number of employees, 2) the professional qualifications of scientists, medical experts, and technical personnel as they relate to the requirements, 3) a description of general and specific facilities and equipment available, including computer equipment and software, and 4) any other specific and relevant information that would improve the Government's consideration and evaluation of the information presented. Further, Past Performance documentation, which should include, but not be limited to, a minimum of two (2) contracts performed for either Government or commercial organizations shall be provided. References shall include for each contract: names, titles, contract number, total price or cost, telephone numbers of government Contracting Officer Representative and Contracting Officers. (c) All capability statements sent in response to this Small Business Sources Sought notice must be submitted electronically (via email) to the Point of Contact below in MS Word or Adobe Portable Document Format (PDF). The subject line must specify NICHD-21-138. Facsimile responses will not be accepted. Electronically submitted capability statements are due no later than 9:00 AM (Eastern Prevailing Time) seven (7) calendar days (including date of submission to https://beta.sam.gov) after posting of the Small Business Sources Sought Notice. CAPABILITY STATEMENTS RECEIVED AFTER THIS DATE AND TIME WILL NOT BE CONSIDERED This notice is for information and planning purposes only and is not to be construed as a commitment by the Government, nor will the Government pay for information solicited.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/0ead4bd93efa439cb3bbe0471263e062/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06022755-F 20210608/210606230109 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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