SOLICITATION NOTICE
66 -- Vinyl Anaerobic Chamber Laboratory Equipment
- Notice Date
- 7/9/2021 10:08:55 AM
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NICHD BETHESDA MD 20817 USA
- ZIP Code
- 20817
- Solicitation Number
- NICHD-21-178
- Response Due
- 7/26/2021 2:00:00 PM
- Archive Date
- 07/30/2021
- Point of Contact
- Jacob Balenson, Phone: 3018278302
- E-Mail Address
-
jacob.balenson@nih.gov
(jacob.balenson@nih.gov)
- Description
- INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION. The National Institutes of Health, National Institute of Child Health and Development (NICHD)� intends to award a purchase order without providing for full and open competition to COY LABORATORY PRODUCTS, INC. for vinyl anaerobic chamber laboratory equipment. BACKGROUND This equipment will be shared between two NICHD labs. The Storz lab studies bacteria and how they survive stress conditions such as low oxygen. They have discovered that stress conditions cause bacteria to produce small regulatory RNA molecules and small proteins. These modify the function of pores that control the flow of nutrients into the cell. The Levin lab studies yeast and how these cells survive conditions of stress. One of the leading features of the genome that mediate this process are transposable elements. These are mobile pieces of DNA that modify the expression of stress response genes and allow cells to adapt to new growth conditions. The Levin lab is currently studying how transposable elements alter gene expression when cells grow in low oxygen conditions. In the case of bacteria, it is known that cells can survive and grow in low oxygen conditions. However, it is not known what small RNAs and proteins function in this pathway. The Storz lab will use this equipment to grow bacteria in low oxygen and will examine the changes in gene expression produced by these conditions. The genes that change expression will be further studied to test whether they function directly in survival. The Levin lab knows from previous work that the expression of transposable elements is greatly increased when cells are grown in low oxygen. The lab wishes to know which genes of yeast are altered by low oxygen and whether the changes in expression are due to transposable elements. Here too, the lab will test altered genes for a direct role in adapting cells to growth in low oxygen. JUSTIFICATION We need vinyl anaerobic chamber laboratory equipment that is designed to reduce oxygen to very low levels, at anerobic ranges from 1 to 5 parts per million. The chamber must be large enough to contain incubator equipment and small lab equipment, such as a centrifuge. The size of the unit must be around� 59� x 32�, sufficiently large enough to allow for our experiments, but not too large to be unable to fit on the bench where it will be placed. The chamber must have an internal incubator for cultures and other space that is not heated, which will allow us to conduct experiments at room temperature. The chamber must also be constructed of vinyl to allow us to have freedom of movement with our arms while inside the chamber gloves. We also require automated oxygen controls that adjust the flow of gas from tanks, because our experiments take place over several days. The chamber must have a vacuum airlock that removes oxygen from air in the lab, this is necessary to introduce materials into the chamber without disturbing the anerobic condition. The chamber must also have an internal dehumidifier to prevent condensation on the surface of the vinyl. The needed low oxygen chamber is a highly complex system that controls the growth environment. Each feature and component have an impact on the performance of the system. Based on our market research and knowledge, there are only two companies that currently produce low oxygen chambers, and COY LABORATORY PRODUCTS, INC.� is the only brand with a product that both uses vinyl and meets all our needs detailed above. The Storz lab has had the current Coy manufactured low oxygen vinyl chamber for many years and conducted key experiments with bacteria using the low oxygen conditions that the chamber produces. The chamber has reached its end of life and now needs to be replaced. If we were to use a chamber from a different manufacturer, then it would certainly introduce a variable that could impact the results of future experiments and confound interpretations regarding the results from our previous work, which would negatively impact our program goals. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 of with a Size Standard of 1,000. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Regulation (FAR) Circular (FAC) 2021-05 effective 3-10-2021.� This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000) and FAR Subpart 12- Acquisition of Commercial Items. STATUTORY AUTHORITY This acquisition is conducted under the authority of FAR Subpart 6.302- FAR 6.302-1�Only one responsible source and no other supplies or services will satisfy agency requirements. PLACE OF PERFORMANCE 9000 Rockville Pike BLDG 49 RM 1A35 Bethesda, Maryland 20892 United States DESCRIPTION OF REQUIREMENT We need vinyl anaerobic chamber laboratory equipment that is designed to reduce oxygen to very low levels, at anerobic ranges from 1 to 5 parts per million with the following: - Large enough to contain incubator equipment and small lab equipment. - Size dimensions around� 59� x 32�. - Include an internal incubator for cultures and other space that is not heated. - Must be constructed of vinyl. - Include automated oxygen controls that adjust the flow of gas from tanks. - Include a vacuum airlock that removes oxygen from air in the lab. - Include an internal dehumidifier to prevent condensation on the surface of the vinyl. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability in response to this notice and may submit a capability statement, proposal, or quotation, which shall be considered by the agency. Responses to this notice shall contain sufficient information to establish the interested parties� bona-fide capabilities for fulfilling the requirement and include unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.� A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses to this notice shall be submitted electronically by 5:00 PM Eastern Standard Time, on July 26th, 2021, to jacob.balenson@nih.gov and shall include solicitation # NICHD-21-178 in the subject line. NOTE TO CONTRACTOR: The contractor shall provide a completed copy of FAR 52.204-24, ""Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment"" with their quote in response to this solicitation.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/469afb3d2d3e4220a7811ac9c94914b3/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06056932-F 20210711/210709230118 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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