SOURCES SOUGHT
66 -- Acquisition of Hypoxystation H35
- Notice Date
- 7/26/2021 1:33:51 PM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NIH NCI ROCKVILLE MD 20852 USA
- ZIP Code
- 20852
- Solicitation Number
- 75N91021Q00190
- Response Due
- 8/3/2021 9:00:00 AM
- Archive Date
- 08/18/2021
- Point of Contact
- David Romley, Phone: 2402767822
- E-Mail Address
-
David.Romley@nih.gov
(David.Romley@nih.gov)
- Description
- SOURCES SOUGHT NOTICE: �Acquisition of Hypoxystation H35 Notice Number: 75N91021Q00190 Issued By: National Cancer Institute (NCI), Office of Acquisitions (OA) http://www.nci.nih.gov�or http://rcb.cancer.gov/rcb-internet/ Key Dates: Capability Statement Due Date: August 3, 2021 by 12:00PM EST This Small Business Sources Sought Notice (SBSS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Cancer Institute (NCI). The purpose of this Sources Sought Notice is to identify qualified Small Business concerns including 8(a), HUBZone or Service-Disabled Veteran-owned businesses that are interested in and capable of performing the work described herein. The NCI does not intend to award a contract on the basis of responses received nor otherwise pay for the preparation of any information submitted. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This requirement is assigned North American Industry Classification System (NAICS) code 334516 with a size standard of 1000 employees. As a result of this Sources Sought Notice, the NCI may issue a Request for Quotation (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME.� However, should such a requirement materialize, no basis for claims against NCI shall arise as a result of a response to this Sources Sought Notice or the NCI�s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. BACKGROUND Radiation therapy is frequently used to treat most cancers. Highly reactive free radicals are produced either directly or indirectly in biological material after irradiation. These radicals are unstable and will react with oxygen to change the chemical composition ultimately causing damage in the target, however, some cancers are less susceptible to radiation and provoke radiotherapy failures. Hypoxic condition, is a common feature of the microenvironment in solid tumors primarily due to an inadequate, and heterogeneous vascular network is associated with resistance to radiotherapy and results in a poorer clinical outcome. The project is to identify and target pathways and molecules associated with failure after radiotherapy for prostate cancer. Hypoxic condition was confirmed in xenograft human prostate tumors, and the levels of hypoxia was increased in prostate tumor after exposure of radiation. It suggests the modulation of hypoxic condition will improve the efficacy of radiotherapy for prostate cancer. To understand various molecular events induced or mediated by hypoxia, hypoxic condition should be generated through controlling the oxygen level tightly during all research procedures in the laboratory. In order to conduct research to better understand the hypoxic condition, a Hypoxystation H35 is necessary. TYPE OF ORDER This will be issued as a Non-Severable Firm Fixed-Price Purchase Order. SPECIAL ORDER REQUIREMENTS PRODUCT FEATURES/SALIENT CHARACTERISTICS The following product features/characteristics are required for this requirement: Double internal power outlets to power small devices that are required for cell culture processing.�� Oval ports allowing maximum arm movement to reach all internal areas of the workstation allowing for maximum usability of the internal workspace. Use of wrist seals as opposed to internal gloves provide much more tactile sense when performing detailed work required with cell culture such as pipetting and passaging cells. Simple latch door closing system that eliminates leaks. Removable front easily replaced within 30 seconds without the use of tools, screws or other loose parts. Humidification system which can be controlled up to 90% Air regulator with 6mm fittings, CO2 regulator with 6mm fittings and a Nitrogen regulator with� 8mm fittings. Specific fitting sizes for attaching tubing. Due to space constraints the unit must fit within these dimensions (W x D x H: 49.5 x 28.5 x 28 inches) Control of O2 in 0.1% increments from 0.1%-20% through the regulator. Control CO2 in 0.1% increments from 0.1%-15% through the regulator. Temperature and gas percentages controlled with a less than 0.1�C and less than 0.1% gradient throughout the workstation to ensure a homogeneous mixture through the entire workstation.� Touch screen interface to monitor all parameters simultaneously. Calibration of gas sensors without moving sensors from the chamber or disrupting the working atmosphere. Integrated oxygen monitoring with oxygen sensor located inside the chamber that provides real time feedback. O2 cell that has two-year life span. Internal gas mixing. Provide laminar air flow inside workstation to ensure proper mixing of internal atmosphere which allows less than 0.1% gradient of gas concentrations and temperature throughout workstation.� Calibration of oxygen sensor via touch screen interface without removing oxygen sensor from workstation environment. Humidification system introduces sterile steam into workstation, user definable up to 90% relative humidity. 12L transfer airlock chamber, which is a 60 second cycle.� Color touch screen control panel for visual display of parameters. Password protected so unauthorized users cannot alter settings The body of the chamber must be 10mm thick annealed acrylic construction (no seams, no welding, no screws, no bolts) Data logging that stores internal conditions for up to 31 days, exportable via USB Large incubation area of 865mm x 430mm x 400mm Ethernet enabled for remote access to touch screen Wireless footswitch (pedal) to control vacuuming and gasing into the workstation. DELIVERY / INSTALLATION/ TRAINING The instrument shall be delivered to the Contracting Officer Representative (COR), within 90 days of purchase order award. Radiation Oncology Branch Bethesda, Maryland, 20892 A minimum 12-month manufacturer warranty must be included Shipping/Handling costs must be included in the quote. NCI will not be�responsible in the event charges are not included in the quote. Installation and training charges must be included in the quote. Note: NCI plans to award a contract that has FOB origin delivery terms. WARRANTY The Contractor shall warrant that any instruments, equipment, components, or other supplies (�Supplies�) procured by this purchase are free of defects in design, material, or manufacture for a period of 12-months from date of installation. The Contractor shall warrant that all consumables or expendable parts are free of defects in design, material, or manufacture for a period of at least 90 calendar days from date of acceptance by the Government. Supplies which are repaired or replaced shall be warranted for the remainder of the initial warranty period or for 90-days�whichever is greater. 12-months of Technical Support shall be included in the warranty. How to Submit a Response: Page Limitations: Interested qualified small business organizations should submit a tailored capability statement for this requirement not to exceed 10 single sided pages including all attachments, resumes, charts, etc. (single spaced, 12-point font minimum) that clearly details the ability to perform the requirements of the notice described above.� All proprietary information should be marked as such.�� Responses should include a minimum of a one page resume of the individuals meeting the requirements, and up to two pages demonstrating experience over the past two years meeting the requirements of this notice.� Statements should also include an indication of current small business status; this indication should be clearly marked on the first page of your capability statement (preferable placed under the eligible small business concern�s name and address).� Responses will be reviewed only by NIH personnel and will be held in a confidential manner. Organizations shall demonstrate 1.) Technical Approach 2.) Personnel Requirements and Organizational Experience. � Due Date:� Capability statements are due no later than August 3, 2021 by 12:00PM EST Delivery Point: All information furnished must be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the unique specifications described herein.� All questions must be in writing and emailed to David.Romley@nih.gov.� A determination by the Government not to compete this requirement based upon responses to this notice is solely within the discretion of the Government.�Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the System for Award Management (SAM) at Beta.SAM.gov. No collect calls will be accepted.�Please reference number 75N91021Q00190 on all correspondence. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a RFQ may be published in beta.SAM.gov. However, responses to this notice will not be considered adequate responses to a solicitation(s). Point of Contact: Inquiries concerning this Notice may be direct to: David Romley at David.Romley@nih.gov. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/98067b4869204d0abd65aba7033f7d37/view)
- Place of Performance
- Address: USA
- Country: USA
- Country: USA
- Record
- SN06073939-F 20210728/210728203301 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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