SOLICITATION NOTICE
65 -- acquisition of a Cytiva AKTA go FPLC
- Notice Date
- 9/13/2021 6:39:45 PM
- Notice Type
- Presolicitation
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NICHD BETHESDA MD 20817 USA
- ZIP Code
- 20817
- Solicitation Number
- NICHD-21-304
- Response Due
- 9/20/2021 6:00:00 AM
- Archive Date
- 10/05/2021
- Point of Contact
- Amber Harris, Fax: 3014803278
- E-Mail Address
-
amber.harris@nih.gov
(amber.harris@nih.gov)
- Description
- INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Office of Acquisitions (OA) on behalf of the on behalf of the National Institute of Digestive, Diabetes & Kidney Diseases intends to award a purchase order without providing for full and open competition (Including brand-name) to GLOBAL LIFE SCIENCES SOLUTIONS USA LLC for the acquisition of a Cytiva AKTA go FPLC and all parts and accessories included. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard of 1,000. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2021-07 Effective September 10, 2021. This acquisition is conducted under the procedures as prescribed in FAR subpart 13�Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000). STATUTORY AUTHORITY This acquisition is conducted under the authority of 41 U.S.C. 253(c) under provisions of the statutory authority of FAR Subpart 6.302- FAR 6.302-1�Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1). PERIOD OF PERFORMANCE Within 30 Days of Award Place of Performance National Institutes of Health� National Institute of Digestive, Diabetes & Kidney Diseases� 5 Memorial Drive Bethesda MD 20892 ? DESCRIPTION OF REQUIREMENT The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports research on many of the most serious diseases affecting public health. The Institute supports much of the clinical research on the diseases of internal medicine and related subspecialty fields, as well as many basic science disciplines.� The Institute's Division of Intramural Research encompasses the broad spectrum of metabolic diseases such as diabetes, obesity, inborn errors of metabolism, endocrine disorders, mineral metabolism, digestive and liver diseases, nutrition, urology and renal disease, and hematology. Basic research studies include biochemistry, biophysics, nutrition, pathology, histochemistry, bioorganic chemistry, physical chemistry, chemical and molecular biology, and pharmacology.� NIDDK extramural research is organized into 4 divisions: Diabetes, Endocrinology, and Metabolic Diseases; Digestive Diseases and Nutrition; Kidney, Urologic, and Hematologic Diseases; and Extramural Activities. �The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, and career development and training awards. The Institute also supports research and development projects and large-scale clinical trials through contracts. _________________________ BACKGROUND The Section on Molecular Virology in the Laboratory of Molecular Biology in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) carries out research on the molecular and structural biology of proteins that are involved in integration of HIV DNA into the host genome. This research requires the purification of large numbers of proteins. FPLC systems are essential equipment for efficient purification of proteins. The system will replace our current Cytiva AKTA Ettan FPLC system (NIH Decal 01682362). The AKTA Ettan system is obsolete and it will soon become difficult to obtain spare parts. Should the system fail before procurement of a replacement system, an important part of our research would be held up. Once the Cytiva AKTA Ettan FPLC system can no longer be used, it will go into surplus. With the AKTA go FPLC system, it will be used for purification of proteins by column chromatography. These proteins, such as HIV-1 integrase, will be used to study the mechanism of how HIV-1 integrate into cellular DNA. PURPOSE AND OBJECTIVES The National Institutes of Health (NIH)�s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has a requirement for an AKTA go FPLC system, which is required for purification of proteins by column chromatography. These proteins, such as HIV-1 integrase, will be used to study the mechanism of how HIV-1 integrates into cellular DNA. The equipment is expected to come with a 1 year warranty and be compatible with our collection of Cytiva chromatography columns and TSK columns. The vendor is expected to set up the equipment in Room 306 of Building 5 at NIH�s Bethesda Main Campus, remove packing materials, and provide user training to Ying Huang and one other member of the laboratory. SALIENT / REQUIRED FEATURES AND SPECIFICATIONS Compatibility with our two existing Cytiva AKTA Pure FPLC systems (NIH Decals 01809890 and 02044543) is an essential requirement. The AKTA go FPLC runs on the same Unicorn software as the AKTA Pure FPLCs. This enables purification software programs to be transferred seamlessly between the three units and avoids having to train users in multiple software packages. This ensures reproducibility regardless of which FPLC is used. This is important because the FPLCs are used by multiple users and the flexibility of being able to switch to another FPLC when one is in use supports the NIDDK mission goals by increasing research efficiency. The AKTA go FPLC system comes with a Micro kit that greatly reduces the volume of the flowpath. This is important because we often have to work with very small samples and a very small dead volume flow path reduces sample loss, dilution and increases resolution. The Micro kit includes an injection valve, conductivity monitor, outlet valve and micro fraction collector nozzle. These components are modular and fully compatible with our AKTA Pure FPLCs, further increasing our options as needs arise in our research work. Specifically, the NIDDK requires the following tasks: Task Area 1 � Installation shall be done within two weeks of delivery on a bench in Room 306 of Building 5 at NIH�s Bethesda Main Campus location. Task Area 2 - The vendor will provide inside delivery. Task Area 3 - Software shall be included together with a 1 year warranty. Task Area 4 - Training will be provided to Ying Huang and one other member of the laboratory. CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted as prescribed in FAR Part 10�Market Research. �Only one source is available: Per FAR 13.106-1(b)(1) the Contracting Officer has determined GLOBAL LIFE SCIENCES SOLUTIONS USA LLC to be the only reasonable available source to provide the Cytiva AKTA go FPLC and all parts and accessories included. �� This acquisition was pursued on a sole source basis centered on the following: The NIDDK studies the detailed properties of biological molecules such as ATPase and kinases in vitro using novel single-molecule fluorescence spectroscopy and microscopy techniques. Understanding how these biomolecules work at the level of individual molecules will bring new insight to a variety of biological processes and thus well-aligned with NIH�s mission. A critical measurement modality developed in the lab is time-resolved fluorescence spectroscopy. These measurements require a piece of electronics capable of recording the arrival times of fluorescence photons with picosecond precision. Furthermore, our research requires 4 independent counting channels with a shared synchronization channel. The HydraHarp 400 from PicoQuant Photonics is the only commercially available system that meets or exceeds all of these specifications and is ideally suited to the needs of our laboratory. Therefore, this order can only be placed with GLOBAL LIFE SCIENCES SOLUTIONS USA LLC. �Failure to procure these deliverables from GLOBAL LIFE SCIENCES SOLUTIONS USA LLC would result in a significant loss of research. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties� bona-fide capabilities for fulfilling the requirement and include: descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all the foregoing requirements, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.� A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses to this notice shall be submitted electronically by 9:00 am Eastern Standard Time, on Monday, September 20, 2021 to the Contracting Officer, Amber Harris, at amber.harris@nih.gov. Assessment of Capability Lowest Price Technically Acceptable �
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/ff9a1738a6534737939e54180fe4b48f/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06131334-F 20210915/210913230129 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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