SPECIAL NOTICE
66 -- 10X Chromium Next GEM Kits
- Notice Date
- 9/24/2021 9:20:44 AM
- Notice Type
- Special Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 75N95021Q00383
- Response Due
- 9/24/2021 11:00:00 AM
- Archive Date
- 10/09/2021
- Point of Contact
- Llakim Dubroff, Phone: 3014436677, Tracy Cain, Phone: 3014436677
- E-Mail Address
-
llakim.dubroff@nih.gov, tracy.cain@nih.gov
(llakim.dubroff@nih.gov, tracy.cain@nih.gov)
- Description
- This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a separate written solicitation will not be issued. The solicitation number is 75N95021Q00383 and the solicitation is issued as a Request for Quotation (RFQ) on a restricted basis, as a BRAND-NAME under the statutory authority FAR Subpart 13.106-1(b) Soliciting from a single source (including brand-name). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13�Simplified Acquisition Procedures; and FAR Part 12�Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. A fixed-price type of purchase order is contemplated for this requirement. THIS IS A NON-COMPETITIVE COMBINED SYNOPSIS SOLICITATION TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2021-07, dated 08/11/2021. The North American Industry Classification System (NAICS) code for this procurement is 334516 - Analytical Laboratory Instrument Manufacturing. This requirement is a small business set aside. This acquisition shall consist of: Background: The National Institute of Neurological Disorders and Stroke (NINDS) intends to purchase Chromium Single Cell Multiome ATAC + Gene Expression Kits, manufactured by 10X Genomics, Inc. The intent of this order is to purchase Chromium Single Cell Multiome ATAC + Gene Expression Kits, manufactured by 10X Genomics, Inc. to measure single cell gene expression and evaluate chromatin accessibility in human normal and tumor cells. The purchase of the specific single cell kits, manufactured by 10X Genomics, Inc., will be used in ongoing research projects. The continued use of the 10X Genomics, Inc. technology is critical in order to maintain the integrity of the data already generated and analyzed. See Attachment 1 � Purchase Description, for additional details. Brand Name Justification: This requirement is for a Brand Name Only acquisition. The Contracting Officer�s Representative conducted market research by having discussions with potential vendors, utilizing beta.sam.gov, GSA Advantage and the internet to identify vendors to purchase Chromium Single Cell Multiome ATAC + Gene Expression Kits, manufactured by 10X Genomics, Inc. to measure single cell gene expression and evaluate chromatin accessibility in human normal and tumor cells. The purchase of the specific single cell kits, manufactured by 10X Genomics, Inc., will be used in ongoing research projects. The continued use of the 10X Genomics, Inc. technology is critical in order to maintain the integrity of the data already generated and analyzed. Market research identified two responsible sources; however, it was found that 10X genomics is the sole company to manufacture of these reagents and these kits are the only kits available which are compatible with NINDS existing 10X genomics equipment. Although other manufacturer�s sequencing kits are available, the use of other kits would jeopardize the integrity, quality and results from this ongoing research project as they would not be compatible with the 10X genomics Chromium instrument. As such, the subject requirement should be met through a total small business set-side, Brand Name Only acquisition. Purchase Description: The Chromium Controller instrument uses advanced microfluidics to perform single cell partitioning and barcoding in a matter of minutes. Powered by Next GEM technology, the Chromium Controller enables integrated analysis of single cells at massive scale. The goal of experiments in using this equipment is to generate single-cell pituitary tumor/normal�libraries on human and mouse samples. For this purpose, the lab needs to have the Chromium Controller machine from 10X Genomics to run samples. Most of the tissues processed in the laboratory are mission-critical human patient derived tissues. Having an in-house single cell embedding and library generation will significantly improve the efficiency and accuracy of these planned experiments. The machine has capability to capture molecular readouts of cell activity in multiple dimensions, including gene expression, cell surface proteins, immune clonotype, antigen specificity, and chromatin accessibility.� This capability is important to the lab research as we study pituitary tumor/normal�libraries on human and mouse samples. The 10X Chromium kits must be used in conjunction with the 10X Chromium equipment as they are compatible with the equipment for consistency and for prevention of experimental data variability.� Quantity: � 1. 1000230 Chromium Next GEM Chip J Single Cell Kit, 16 rxns �������� Quantity #1 2. Chromium Next GEM Chip J Single Cell Kit, 48 rxns Quantity #3 3. Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, 16 rxns Quantity #3 4. Chromium Next GEM Single Cell Multiome ATAC + Gene Expression Reagent Bundle, 4 rxns Quantity #1 Salient characteristics:� The kits are compatible with the Chromium Instrument and therefore no other kits can be used for these experiments and for the purposes described above. ��� � �� � � � � � � � � � � � � � � � � � � � � � � � � � Delivery Date: Within 30 days of award. The contractor shall deliver all kits between the hours of 8:00am and 5:00 pm, Bethesda, MD local prevailing time at 10 Center Drive, Room 5C103, MSC 1400, Bethesda, MD 20892. Extra training is not required to be included. The kit shall be delivered in ice, dry ice, and room temperature (conditions are indicated above) to maintain the temperature. Period of Performance: The shelf life for the kit are 3-12 months, entire kits are planned to be used in 12 months as samples are ready to be processed. The Chromium controller has a 12 month warranty. Delivery shall be to: Mary Kiganda National Institute of Neurological Disorders and Stroke NIHBC 35A - PNRC II BG Rm GF-140 35A Convent Dr Bethesda Md 20892 Delivery shall be according to the requirements set forth in the Purchase Description. The provision at FAR Clause 52.212-1 Instructions to Offerors�Commercial Items is applicable to this solicitation. The provision at FAR clause 52.212-2, Evaluation � Commercial Items, applies to this acquisition. The following is provided as an addendum to clause 52.212-2: (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, i.e. this RFQ will be evaluated on the basis of Lowest-Price Technically-Acceptable (LPTA). Offeror�s submitting a response must provide a completed Price Quote to be evaluated and considered for award. Price quotes must indicate fixed unit pricing and total cost, including shipping cost and estimated time of delivery after receipt of order, and warranty and training considerations. Under the lowest-price technically acceptable (LPTA) process, Offerors� will be determined to be �technically acceptable� or �technically unacceptable� based on an evaluation of responses against the following factors to determine if, as submitted, the proposal is technically acceptable. Award will be made to the lowest-priced, technically acceptable, responsible offeror. Technical acceptability shall be based on the following: The Offeror must indicate in its quotation the ability to provide all the requirements as specified in the Purchase Description. The Offeror must indicate in its quotation the ability to meet the delivery requirements as specified in the Purchase Description. A written notice of award or acceptance of an offer mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer�s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. Responses to this solicitation must include clear and convincing evidence of the Offeror�s capability of fulfilling the requirement as it relates to the technical evaluation criteria. Offerors may respond with a proposal indicating their ability to provide the technical specifications stated in this solicitation. Responses will be evaluated based on the contractor�s ability to meet the government�s requirements. The Offeror is to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications�Commercial Items, with its offer. The provision at FAR Clause 52.212-4, Contract Terms and Conditions�Commercial Items, applies to this acquisition. See Attachment 2 � Commercial Contract Terms and Conditions. The provision of FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items, applies to this acquisition. See Attachment 2 � Commercial Contract Terms and Conditions. The Contractor shall comply with the following Federal Acquisition Regulation (FAR) clauses, which are incorporated in this contract by reference, to implement provisions of law or Executive orders applicable to acquisitions of commercial items: FAR 52.203-19, Prohibition on Requiring Certain Internal Confidentiality Agreements or Statements (Jan 2017) (section 743 of Division E, Title VII, of the Consolidated and Further Continuing Appropriations Act, 2015 (Pub. L. 113-235) and its successor provisions in subsequent appropriations acts (and as extended in continuing resolutions)). FAR 52.204-23, Prohibition on Contracting for Hardware, Software, and Services Developed or Provided by Kaspersky Lab and Other Covered Entities (Jul 2018) (Section 1634 of Pub. L. 115-91). FAR 52.204-24, Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment. (Oct 2020). FAR 52.204-25, Prohibition on Contracting for Certain Telecommunications and Video Surveillance Services or Equipment. (Aug 2020). FAR 52.209-10, Prohibition on Contracting with Inverted Domestic Corporations (Nov 2015). FAR 52.233-3, Protest After Award (Aug 1996) (31 U.S.C. 3553). FAR 52.233-4, Applicable Law for Breach of Contract Claim (Oct 2004) (Public Laws 108-77 and 108-78 (19 U.S.C. 3805 note)). FAR 52.232-39 Unenforceability of Unauthorized Obligations (JUN 2013) The Contractor shall comply with the following FAR clauses: 52.204-10 Reporting Executive Compensation and First-Tier Subcontract Awards (Oct 2016) 52.219-28 Post Award Small Business Program Representation (JUL 3013) 52.222-3 Convict Labor (June 2003). 52.222-19 Child Labor�Cooperation with Authorities and Remedies (Oct 2016) 52.222-21 Prohibition of Segregated Facilities (Apr 2015). 52.222-26 Equal Opportunity (Sept 2016). 52.222-36 Equal Opportunity for Workers with Disabilities (JUL 2014) 52.222-40, Notification of Employee Rights Under the National Labor Relations Act (DEC 2010) 52.222-50 Combating Trafficking in Persons (March 2015) 52.223-18 Encouraging Contractor Policies to Ban Text Messaging While Driving (Aug 2011) 52.225-13 Restrictions on Certain Foreign Purchases (June 2008) 52.232-33 Payment by Electronic Funds Transfer� System for Award Management (JUL 2013). The following additional contract requirement(s) or terms and conditions as determined by the contracting officer are necessary for this acquisition and consistent with customary commercial practices. Attachment 1 � Purchase Description Attachment 2 � Commercial Contract Terms and Conditions Attachment 3 � Invoice Instructions The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties� bona-fide capabilities of providing the product or service. The technical response and price quote shall be submitted in an order and manner consistent with evaluation factors described and the attached Purchase Description. The response to the combined synopsis/solicitation is due no later than September 25, 2021 at 1:00 P.M. Eastern Standard Time (EST). Proposal submitted after the deadline may not be considered. The response must be submitted in a �read-only� electronic format to the Contract Specialist, Llakim Dubroff, at Llakim.dubroff@nih.gov. In the response, Offerors shall cite the RFQ number 75N95021Q00383 and the name of firm in the subject line of email submittal. Fax responses will not be accepted. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. Request for additional information and clarification may be sent to Contract Specialist, Llakim Dubroff, at Llakim.dubroff@nih.gov on or before September 24th at 1:00 P.M EST.
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/88b30d1d6fee48799ac2a183c8abab9f/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06143655-F 20210926/210925200937 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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