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SAMDAILY.US - ISSUE OF NOVEMBER 04, 2021 SAM #7278
SPECIAL NOTICE

A -- Intent to Sole Source: Investigational New Drug Request - Imiquid & Placebo cream

Notice Date
11/2/2021 6:22:58 AM
 
Notice Type
Special Notice
 
NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 
Contracting Office
RPO EAST (36C24E) PITTSBURGH PA 15212 USA
 
ZIP Code
15212
 
Solicitation Number
36C24E22Q0013
 
Archive Date
02/09/2022
 
Point of Contact
Lynn M Portman, lynn.portman@va.gov, Phone: (412) 822-3442
 
E-Mail Address
lynn.portman@va.gov
(lynn.portman@va.gov)
 
Awardee
null
 
Description
Page 1 of 1 The Department of Veterans Affairs, VA Cooperative Studies Program, Clinical Research Pharmacy Coordinating Center (CRPCC) in Albuquerque, NM, intends to negotiate on a sole source basis, pursuant to FAR 6.302-1, with Irisys Inc provide ACTIVE Imiquimod 5% cream and matching PLACEBO products to CRPCC for up to a three-year period. The vendor is also required to develop required formulations and analytic methods related to successful manufacturing of the product which will be submitted to the FDA as part of the Investigational New Drug (IND) request. Irisys was the only vendor identified who was a FDA-approved Manufacturer and could formulate, manufacture, and supply the CSPCRPCC with active Imiquimod (IMQ) 5% topical cream with a therapeutic equivalence evaluation and a matching placebo and the vendor. Therapeutic equivalency requires that the active IMQ 5% cream be classified as a pharmaceutical equivalent, expected to have the same clinical effect and safety profile when administered to study participants under the conditions specified in the official prescribing information. Irisys will develop active and placebo formulations and provide it to user for submission in FDA Investigational New Drug (IND) application. This requirement is supporting a cancer prevention clinical study intending to use imiquimod 5% cream and matching placebo as the drug intervention. This trial will study the effects of chemoprevention on the recurrence of basal cell carcinoma. This is a notice of intent and is not a request for competitive proposals; however, any responsible source who believes it is capable of meeting the requirement may submit a capability statement to the contracting office no later than November 9th, 12PM, EST. Interest/capability statements may be sent to Lynn Portman at lynn.portman@va.gov. No telephone responses will be accepted. A determination not to compete the proposed requirement based upon the responses to this notice is solely within the discretion of the Government.
 
Web Link
SAM.gov Permalink
(https://beta.sam.gov/opp/97b00f69d75f40708922a762d23164f8/view)
 
Record
SN06168896-F 20211104/211102230112 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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