SOURCES SOUGHT
66 -- Chromium Consumables
- Notice Date
- 3/31/2022 12:43:44 PM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- HHS-NIH-NIDA-SSSA-75N95022Q00179
- Response Due
- 4/15/2022 7:00:00 AM
- Point of Contact
- fred Ettehadieh
- E-Mail Address
-
fred.ettehadieh@nih.gov
(fred.ettehadieh@nih.gov)
- Description
- This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. (4) availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. For equipment/supply requirements, small business responses must include: (1) the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture), as well as (2) the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule). Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.� It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.� Responses will not be considered as proposals or quotes.� No award will be made as a result of this notice.� The Government will NOT be responsible for any costs incurred by the respondents to this notice.� This notice is strictly for research and information purposes only. This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition.� It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.� Responses will not be considered as proposals or quotes.� No award will be made as a result of this notice.� The Government will NOT be responsible for any costs incurred by the respondents to this notice.� This notice is strictly for research and information purposes only. Background: The 10X Genomics Chromium system enables researchers in the Laboratory of Genomics and Genetics, National Institute on Aging (LGG/NIA)� to capture between 10,000 to 80,000 single cells, mark them with a bar-code and a second unique molecular code that can be tagged to genomic DNA, or RNA.� Following downstream procedures to isolate DNA or RNA and sequencing, these unique codes are read, deconvoluted and stratified to learn the nature of transcripts or status of DNA within each captured single cell.� This procedure is highly valuable to distinguish the cellular complexity of a tissue based on the nature of transcription profile, identify DNA status in individual cells in terms of its DNA accessibility for transcription, nature of insertions and deletions. There is a wide interest in the field to understand the composition of solid and hematopoietic tissues and define the nature of resident stem cells and their fate during aging. The method helps to distinguish cell types with different functions, which can then be marked with specific antibodies and followed during development, differentiation and aging.� This method will allow us to approach these goals with high efficiency. It is important to note that this system is much more �automatized� than other available methods, so that it is correspondingly more likely to get dependable data from precious samples.� Purpose and Objectives: The essential characteristics of the 10X genomics Chromium System that limit the availability to a sole source are ability to collect single cells mark them such the DNA and and RNA isolated from these cells are tagged with an unique tag and allows one to assess the differences in cell population isolated from a tissue or tumor and identify cell heterogenieity.� Only this suggested source can furnish the requirements, to the exclusion of other sources, because this sytem can isolate >10,000 cells in a single lane and using 8 lanes available on the chip it can isolate up to 80,000 cells.� The system is provided with software to analyze the resulting transcription profiles and score variants.� Project requirements: The contractor shall provide the following: 1000256 - 5' Feature Barcode Kit, 16 rxns 1000190 - Library Construction Kit, 16 rxns 1000263 - Chromium Next GEM Single Cell 5' Kit v2, 16 rxns 1000286 - Chromium Next GEM Chip K Single Cell Kit, 48 rxns Anticipated period of performance: 4-6 weeks after Award of Order (ARO). Capability statement /information sought: Small business concerns that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately.� Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Small businesses must also provide their Company Name, DUNS number, Physical Address, and Point of Contact Information. Interested small businesses are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, reference the solicitation notice number. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2� x 11� paper size, with 1� top, bottom, left and right margins, and with single or double spacing. The information submitted must be in an outline format that addresses each of the elements of the project requirements and in the capability statement /information sought paragraphs stated herein.� A cover page and an executive summary may be included but is not required. The response is limited to ten (10) pages.� The 10-page limit does not include the cover page, executive summary, or references, if requested. All capability statements sent in response to this Small Business Sources Sought Notice must be submitted to Fred Ettehadieh, Contracting Officer, by email at fred.ettehadieh@nih.gov before the closing date and time of this announcement. All responses must be received by the specified due date and time in order to be considered. Facsimile responses are not acceptable. ��Disclaimer and Important Notes:� This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).�
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/99c52032e5ba4f27bbdcb3020d9dcbe2/view)
- Place of Performance
- Address: MD, USA
- Country: USA
- Country: USA
- Record
- SN06286887-F 20220402/220331230115 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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