Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF JULY 01, 2022 SAM #7518
SOLICITATION NOTICE

B -- PILOT STUDY TO IDENTIFY RISK FACTORS FOR SUSCEPTIBILITY TO ANTHRAX AND EVALUATE ANTITOXIN EFFECTIVENESS FOR SYSTEMIC ANTHRAX

Notice Date

6/29/2022 12:10:09 PM
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 

Contracting Office

CDC CENTER FOR GLOBAL HEALTH Atlanta GA 30333 USA
 

ZIP Code

30333
 

Solicitation Number

RFQ75D30122Q74843
 

Response Due

7/12/2022 11:00:00 AM
 

Archive Date

07/27/2022
 

Point of Contact

Saulat Rehan, Phone: 6784754500
 

E-Mail Address

srehan@cdc.gov
(srehan@cdc.gov)
 

Description

The purpose of this requirement is to work in an anthrax endemic area with high standards of in-hospital medical care to 1) collect data on clinical outcomes of an antitoxin in the group for whom it would be indicated in the US, i.e., patients with systemic anthrax; 2) assess the prevalence of oxidatively stressing common chronic diseases and exposures so that the Government can later design a case-control study to identify demographic, dietary, or social (e.g., smoking, drinking) variables or comorbidities that might serve as risk factors for anthrax morbidity and mortality; and 3) collect, store, and characterize isolates determined to exhibit antimicrobial resistance by correlating whole genome sequence changes to resistance levels (Broth Microdilution). Understanding 1) how well antitoxins work in a hospital setting, 2) whether any conditions or habits increase risk for B. anthracis infection, and 3) whether there are natural factors that contribute to the development of resistance will enhance USG biopreparedness for a wide-area release of B. anthracis. The Kyrgyz Republic, which is endemic for anthrax, regularly identifies human anthrax cases.� Treatment protocols are standardized and a consistent level of care is provided to patients with anthrax diagnoses. Moderate to severe cases are diagnosed annually, which is the target group for receiving antitoxin; because all anthrax cases are hospitalized, administration of antitoxin and collection of biomarker data is more possible than it would be in other anthrax-endemic countries with less developed healthcare infrastrucutre. Care is more consistent with US treatment protocols compared to treatment practices in many other anthrax-endemic countries.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/1a8be9e24ebe41afbe7458d86423deca/view)
 

Place of Performance

Address: Atlanta, GA 30333, USA

Zip Code: 30333

Country: USA
 

Record

SN06372998-F 20220701/220629230104 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

---

| FSG Index  |  This Issue's Index  |  Today's SAM Daily Index Page |