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SAMDAILY.US - ISSUE OF JULY 29, 2022 SAM #7546
MODIFICATION

66 -- Flash Purification Chromatography System with Automated Mass Directed Fraction Collection

Notice Date
7/27/2022 1:16:49 PM
 
Notice Type
Combined Synopsis/Solicitation
 
NAICS
334516 — Analytical Laboratory Instrument Manufacturing
 
Contracting Office
NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
 
ZIP Code
20892
 
Solicitation Number
75N95022Q00452
 
Response Due
8/4/2022 9:00:00 AM
 
Archive Date
08/19/2022
 
Point of Contact
Sarah Adan, Phone: 3014805422, Valerie Whipple
 
E-Mail Address
sarah.adan@nih.gov, valerie.whipple@nih.gov
(sarah.adan@nih.gov, valerie.whipple@nih.gov)
 
Description
Chemists of the National Center for Advancing Translational Sciences (NCATS) confirm the mass of compounds eluting in fractions collected during flash silica gel purification by manually taking aliquots from several fractions, entering these aliquots to separately located reverse phase LCMS systems, and then waiting for LCMS results to determine what fractions contain compounds of their interest. The Flash Purification Chromatography System will be a dedicated normal flash purification system that will not only collect fractions based on UV but also acquire the mass spectrum of compounds while they are being eluted into fractions. This will significantly cut down the manual step of acquiring the LCMS separately of fractions in order to verify the identity of the compounds. The purpose of this acquisition is to acquire one (1) of Biotage�s Isolera + Dalton 2000 System or Equal that meet all salient characteristics.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/842190e063504f1c8cb572ba7f190d9a/view)
 
Record
SN06403195-F 20220729/220727230112 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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