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SAMDAILY.US - ISSUE OF AUGUST 18, 2022 SAM #7566
SOLICITATION NOTICE

A -- CRISPR Knockout Libraries

Notice Date
8/16/2022 1:10:16 PM
 
Notice Type
Presolicitation
 
Contracting Office
NATIONAL INSTITUTE OF HEALTH NIEHS MORRISVILLE NC 27560 USA
 
ZIP Code
27560
 
Solicitation Number
NIEHS-6440705-TR
 
Response Due
8/18/2022 12:30:00 PM
 
Point of Contact
Tanya Redfearn, Phone: 984-287-3052
 
E-Mail Address
shields3@niehs.nih.gov
(shields3@niehs.nih.gov)
 
Description
THIS IS A NOTICE OF INTENT TO AWARD A SOLE SOURCE ORDER AND NOT A REQUEST FOR QUOTATIONS. This contract action is for the acquisition of Services for which the Government intends to solicit and negotiate with only one source under the authority of Federal Acquisition Regulation (FAR) Subpart 13.106-l(b). The National Institute of Environmental Health Sciences (NIEHS), Office of Acquisitions (OA) intends to award a single source purchase order to Sigma-Aldrich, Inc. 3050 Spruce St. Saint Louis MO 63103-5473, for the acquisition of CRISPR Knockout Libraries. The NIEHS DIR requires arrayed CRISPR Knockout libraries, delivered as glycerol stocks. NIEHS require separate libraries for all human genes and all mouse genes. The NIEHS also wishes to provide capability to reduce expression of a specific panel of genes involved in epigenetic regulation using CRISPRi. NIEHS will provide a list of target genes, control genes, and non-targeting controls to the vendor. NIEHS require a vector backbone that includes the antibiotic resistance marker of our choice, the fluorescent protein of our choice, and that does not contain Cas9. The vendor will design 4 guide RNAs per target using the algorithm of their choice. The panel will be delivered as glycerol stocks in arrayed format with one guide RNA per well. ������������������������������������������������������� MATERIAL NUMBER������������������������������ 001� �����1 EA����������� CSTGLY MISSION SHRNA CUSTOM GLYCEROL� 002 ������1 EA �������������HSANGER WHOLE HUMAN GENOME CRISPR LIBRARY, GLYCEROL 003 ������1EA �������������MSANGER WHOLE MOUSE GENOME CRISPR LIBRARY, GLYCEROL ������������������ The applicable North American Industry Classification System (NAICS) code for this acquisition is 325412 � �Pharmaceutical Preparation Manufacturing"" and a size standard of employees 1250. NIEHS will solicit and negotiate directly with Sigma-Aldrich, Inc. and no solicitation will be issued.� This notice of intent is not a request for competitive proposals or quotations; however, an interested party may submit a statement of capabilities if they believe they can meet the above requirement.� The statement of capabilities must be submitted in writing and contain sufficient detail to allow the Government to determine if the party can provide the requirement.� A determination by the Government not to compete this proposed action based upon responses to this notice is solely with the discretion of the Government. �All responses must be received within (3) days from the date of publication of this synopsis.� Information received will normally be considered for the purpose of determining whether to conduct a competitive procurement.� If no affirmative responses are received within (3) days of this notice, an award will be made to Sigma-Aldrich, Inc.� This procurement is to be processed using Simplified Acquisition Procedures.� There is no solicitation package available.� No faxed documents will be accepted.� For any questions regarding this announcement, please contact Tanya Redfearn via email: shields3@niehs.nih.gov.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/198f4c2657644768b7efa1307f2183f9/view)
 
Record
SN06428436-F 20220818/220816230119 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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