Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF AUGUST 24, 2022 SAM #7572
SPECIAL NOTICE

66 -- Multiclamp amplifier and Digidata analog to digital converter, with required software,

Notice Date

8/22/2022 11:19:17 AM
 

Notice Type

Special Notice
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

NATIONAL INSTITUTES OF HEALTH OLAO BETHESDA MD 20892 USA
 

ZIP Code

20892
 

Solicitation Number

NIH-SS-6420329
 

Response Due

8/27/2022 6:00:00 AM
 

Point of Contact

Ryan Alexander
 

E-Mail Address

ryan.alexander@nih.gov
(ryan.alexander@nih.gov)
 

Small Business Set-Aside

8AN 8(a) Sole Source (FAR 19.8)
 

Description

Project Title : Purchase of a Multiclamp amplifier and Digidata analog to digital converter, with required software, from Molecular Devices to record and analyze electrical signals from single neurons for neuroscience research. The system is manufactured by Molecular Devices. Project Description: This electrical equipment is required for patch-clamp electrophysiology experiments that provide the basis for experiments to investigate synaptic contacts and electrical activity in single neurons in the auditory system of mice, which have similar auditory circuitry to humans. The system allows measurement of the minute electrical signals in single live neurons, and thus allows investigation of the function of these neurons in the brain. Project Background: The Section on Neuronal Circuitry in the NIDCD seeks to understand neurons that originate in the brainstem, but project to the cochlea, and modulate auditory perception. The neurons are implicated in protection from noise trauma, detection of sounds in noise (hearing speech in a noisy room), as well as altered functions in pathological auditory conditions such as in tinnitus or hyperacusis. The research involves studying the electrical activity of single neurons in the brain and cochlea, as well as the interaction of these neurons with other neurons. This requires microscopes and electrical equipment to visualize the neurons for experiments, as well as the electrical equipment that is specialized for recording the minute electrical signals that occur in single neurons. This amplifier, digidata, and software comprise the equipment used for these electrical measurements for ongoing projects within the lab, and therefore must integrate with existing equipment. We currently have two identical systems, and accessories must be interchangeable between the systems. Therefore, we require Molecular Devices amplifiers / digidata and associated software, specifically the Multiclamp 700B amplifier, Digidata 1550B1, and pClamp 11 software that is being requested. Requirements: (See Attached) System is required to be fully interchangeable with three existing systems that all utilize a multiclamp 700B system, digidata 1550, and pClamp 11 software
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/df09fb90ffff44d8ad7e334500b07400/view)
 

Place of Performance

Address: Bethesda, MD 20892, USA

Zip Code: 20892

Country: USA
 

Record

SN06435625-F 20220824/220823060732 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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