SAMDaily.us | PRESOL | Q | PK mouse IV, PO AND IP study at 3 concentrations

SAMDAILY.US - ISSUE OF MARCH 02, 2023 SAM #7765
SOLICITATION NOTICE

Q -- PK mouse IV, PO AND IP study at 3 concentrations

Notice Date: 2/28/2023 4:53:10 PM
Notice Type: Combined Synopsis/Solicitation
NAICS: 325414 — Biological Product (except Diagnostic) Manufacturing
Contracting Office: NATIONAL INSTITUTES OF HEALTH NCATS BETHESDA MD 20892 USA
ZIP Code: 20892
Solicitation Number: 75N95C23P00038
Response Due: 3/9/2023 2:00:00 PM
Archive Date: 03/24/2023
Point of Contact: Rhanda Lopez
E-Mail Address: rhanda.lopez@nih.gov
(rhanda.lopez@nih.gov)
Description: This service should provide the following deliverables: 1. Properly formulate the compound for IV, IP and PO administration to mice in 3, 10 and 30 mg/kg concentrations respectively. 2. Run a� mouse PK study in B57BL6 mice for the compounds at 3, 10 and 30 mg/kg concentrations, analyzing heart, brain, lung, plasma and liver. 3. For each compound dose, complete PK analysis at 6 time points through 24 hours with n=6 in tissues of interest: plasma, bone, liver, heart, brain.
Web Link: SAM.gov Permalink
(https://sam.gov/opp/69e63f2d0328487db066f355d5d28462/view)
Place of Performance: Address: Louisville, KY 40202-1249, USA; Zip Code: 40202-1249; Country: USA
Record: SN06603643-F 20230302/230228230107 (samdaily.us)
Source: SAM.gov Link to This Notice
(may not be valid after Archive Date)

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