SOLICITATION NOTICE
65 -- 3D Liver Microstissues Composed of Human Primary Hepatocytes and a Mixture of Human Primary Hepatocyte, Liver Endothelial Cells and Kupffer Cells
- Notice Date
- 5/10/2023 1:41:09 PM
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 325414
— Biological Product (except Diagnostic) Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 75N95023Q00181
- Response Due
- 5/15/2023 12:00:00 PM
- Archive Date
- 05/15/2023
- Point of Contact
- Chandani Hangilipola, Phone: 13014807089
- E-Mail Address
-
chandani.hangilipola@nih.gov
(chandani.hangilipola@nih.gov)
- Description
- The National Center for Advancing Translational Sciences (NCATS) 3D Tissue Bioprinting Laboratory is assembling a portofilio of 3D tissue models in microplate format that can be used for drug testing. In order to accelerate the creation of a ready to use tissue platforms to be able to rapidly respond to health care crisis, like the COVID-19 pandemic, the 3D Tissue Bioprinting laboratory develops its own tissue models, but also looks for opportunities with 3D tissue models that are commercially available, well validated and ready to use. A contractor has indentified by scienitsts at the 3DTBL as a company that produces live fucntional 3D liver microtissues, in a ready to use HTS compatible multiwell plate format. NCATS will use these 3D liver microtissues composed of human primary hepatocytes and a mixture of human primary hepatocyte, liver endothelial cells and kupffer cells to to study viral infectivity, effects of viral infectivity on liver fucntion biomarkers, and effect of anti-viral compounds on viral infection.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/113755233be74b95b506ecad7255f299/view)
- Record
- SN06678545-F 20230512/230510230116 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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