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SAMDAILY.US - ISSUE OF JUNE 25, 2023 SAM #7880
SOLICITATION NOTICE

65 -- Identify modifiers of SMCHD1 activity in human cranial placode cells for the National Institute on Translational Sciences (NCATS)

Notice Date
6/23/2023 12:38:27 PM
 
Notice Type
Presolicitation
 
NAICS
541714 — Research and Development in Biotechnology (except Nanobiotechnology)
 
Contracting Office
NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
 
ZIP Code
20892
 
Solicitation Number
75N95023Q00426
 
Response Due
6/30/2023 1:00:00 AM
 
Archive Date
07/15/2023
 
Point of Contact
Nick Niefeld, Phone: 3018272094
 
E-Mail Address
nick.niefeld@nih.gov
(nick.niefeld@nih.gov)
 
Small Business Set-Aside
SBA Total Small Business Set-Aside (FAR 19.5)
 
Description
NOTICE OF INTENT to Sole Source SOLICITATION NUMBER: 75N95023Q00246 TITLE: �Identify modifiers of SMCHD1 activity in human cranial placode cells CLASSIFICATION CODE: 6505 � Drugs and Biologicals NAICS CODE: 541714 � Research and Development in Biotechnology (except Nanobiotechnology) RESPONSE DATE: June 30, 2023, 4:00 pm EST PRIMARY POINT OF CONTACT: Nick Niefeld���� Nick.niefeld@nih.gov Phone: 301.827.2094 DESCRIPTION: INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). National Center for Advancing Translational Sciences (NCATS) intends to negotiate on a sole source basis with Synthego, Corp for Identify modifiers of SMCHD1 activity in human cranial placode cells NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE and SET ASIDE STATUS The intended procurement is classified under NAICS code 514741 � Research and Development in Biotechnology (except Nanobiotechnology) with a Size Standard of 1,000 Employees. � REGULATORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13�Simplified Acquisition Procedures. Contracts awarded using FAR Part 13�Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6�Competition Requirements. FAR Subpart 13.106-1 (b) Soliciting from a single source provides that: For purchases not exceeding the simplified acquisition threshold, Contracting Officers may solicit from one source IF the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, brand-name OR industrial mobilization). The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2023-04 dated June 2, 2023. DESCRIPTION OF REQUIREMENT PURPOSE AND OBJECTIVES: The purpose of this requirement is to Identify modifiers of SMCHD1 activity in human cranial placode cells from Synthego Corp CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME) DETERMINATION The FGL requires the services of Synthego to meet project milestones. Synthego�s services portfolio includes a large selection of gene editing services that allow for the knock-in of reporter tags at specific gene regions in stem cells. The services offered that are of interest to the FGL include: CRISPR-Edited human H9 Stem Cells � using a robust, automated CRISPR editing process that delivers consistently high editing in virtually any cell type. Synthego has over 60,000 edits completed and characterized. This expertise is applied to stem cell editing to achieve unprecedented editing efficiencies of the highest quality. They offer knockouts, single nucleotide variants, and tags in user-supplied stem cell lines available in homozygous or heterozygous clone or pool format. These services will be utilized by the FGL to obtain reporter cell lines that will facilitate the development of stem differentiation protocols. The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, Synthego Corp., is the only vendor in the marketplace that can provide the services required by NCATS in the interest of continuity of science The intended source is: Synthego Corp 3696 Haven Ave, Suite A - Redwood City, CA 94063 CLOSING STATEMENT THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. All responsible sources may submit a capability statement, proposal, or quotation which shall be considered by the agency. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity ID (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by the closing date and time of this announcement and must reference the solicitation number 75N95023Q00426. Responses must be submitted electronically to Nick Niefeld, Contract Specialist, at nick.niefeld@nih.gov. U.S. Mail and fax responses will not be accepted.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/1e8294486e3f4eb7927928d4dde33f08/view)
 
Place of Performance
Address: CA, USA
Country: USA
 
Record
SN06726611-F 20230625/230623230117 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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