Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF JUNE 29, 2023 SAM #7884
SPECIAL NOTICE

B -- Antibacterial Compound Optimization_NOI

Notice Date

6/27/2023 11:59:03 AM
 

Notice Type

Special Notice
 

NAICS

541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 

Contracting Office

ARMY MED RES ACQ ACTIVITY FORT DETRICK MD 21702 USA
 

ZIP Code

21702
 

Solicitation Number

PANMRA-23-P-0000_004865
 

Response Due

7/11/2023 7:00:00 AM
 

Archive Date

07/26/2023
 

Point of Contact

Linda Hinson, Sharew Hailu
 

E-Mail Address

linda.t.hinson.civ@health.mil, sharew.hailu.civ@health.mil
(linda.t.hinson.civ@health.mil, sharew.hailu.civ@health.mil)
 

Description

THIS IS A NOTICE OF INTENT TO AWARD A SOLE-SOURCE CONTRACT AND IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. The U.S. Army Medical Research Acquisition Activity (USAMRAA) intends to award a sole source basis in accordance FAR 6.302-1 with George Mason University (GMU), Fairfax, VA. as the only responsible source that can provide specialized and optimized antibacterial compounds, in support of the Bacterial Disease Branch (BDB) at Walter Reed Institute of Research (WRAIR) located in Silver Spring MD. This acquisition is being conducted under FAR Part 15.� Objectives �The contractor shall synthesize proprietary antibacterial compounds (CT-AP1) for delivery to WRAIR. �The contractor shall synthesize optimized antibacterial compounds for delivery to WRAIR.� Specific Tasks / Requirements �The contractor shall synthesize proprietary antibacterial compounds (CT-AP1) for delivery�� to WRAIR for testing in in vitro assays and x-ray crystallography experiments.� The contractor shall perform multiple rounds of synthetic synthesis of novel/optimized� antibacterials within 2-4 months. The contractor shall synthesize the antibacterial compounds, using structural data and structure-activity relationship data employing their knowledge of chemistry, organic chemistry, medicinal chemistry, and associated laboratory techniques and skills. The contractor shall deliver the optimized synthesized compounds to WRAIR within 1-4 weeks after receiving data from WRAIR. The contractor shall provide a monthly progress report including data and results on relevant tasks performed� WRAIR will conduct assay tests including enzyme inhibition, biofilm inhibition and minimum inhibitory concentration (MIC) assays. Assay data will be sent back to contractor and process will repeat until MIC of 1�g/mL is achieved. All compounds shall be shipped to WRAIR with a certificate of analysis indicating at least 95% purity and at least 10mg quantities within 1-4 weeks after receiving data from WRAIR.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/91a5bc7eb01649d9ae8b5f7c4186db07/view)
 

Place of Performance

Address: Silver Spring, MD 20910, USA

Zip Code: 20910

Country: USA
 

Record

SN06728907-F 20230629/230627230040 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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