SOLICITATION NOTICE
66 -- Synergy Neo2 Hybrid Multi-Mode Microplate Reader and Accessories
- Notice Date
- 8/16/2023 12:59:01 PM
- Notice Type
- Combined Synopsis/Solicitation
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIAID BETHESDA MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- RFQ-NIAID-23-2174941
- Response Due
- 8/25/2023 1:00:00 PM
- Archive Date
- 09/09/2023
- Point of Contact
- DIANA ROHLMAN, Phone: 4063639366, Laura Grey, Phone: 4063759812
- E-Mail Address
-
diana.rohlman@nih.gov, laura.grey@nih.gov
(diana.rohlman@nih.gov, laura.grey@nih.gov)
- Description
- This notice is a combined synopsis/solicitation for commercial items using Simplified Acquisition Procedures. This acquisition will be made in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 12.6 �Streamlined Procedures for Evaluation and solicitation for commercial Items,� as applicable, and as supplemented with additional information included in this notice. This announcement constitutes the only solicitation (a written solicitation will not be issued) and quotes are being requested. The Solicitation number is RFQ-NIAID-23-2174941 and the solicitation is issued as a Request for Quotes (RFQ). This acquisition will be processed under FAR Part 13 Simplified Acquisition Procedures (SAP). The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2023-04 June 2, 2023.� The North American Industry Classification System (NAICS) code for this procurement is 334516, Analytical Laboratory Instrument Manufacturing, with a size standard of 1000 employees. The requirement is being competed with a brand name restriction, and without a small business set-aside. The research in the Laboratory of Immunogenetics (LIG) focuses on the cellular and molecular mechanisms that underlie the signaling functions of immune cell receptors. This work encompasses a wide spectrum of experimental approaches from the structural determination of immune receptors to live-cell image analysis of the behavior of chemotactic receptors.LIG members are highly interactive, creating a unique environment in which structural biology, molecular, and cell biology are interfaced. Interactions within LIG are facilitated by weekly work-in-progress presentations detailing recent advances and future directions of LIG fellows and students. I.�� �Project Description: he Antibody Biology Unit (ABU) of the Laboratory of Immunogenetics (LIG), in furtherance of its mission to advance our knowledge of human B cells and isolation of monoclonal antibodies requires a high-throughput microplate reader capable of detecting UV-Vis absorbance, fluorescence intensity and polarization, time-resolved fluorescence, luminescence, and alpha while maintaining specific incubation temperature and CO2 parameters necessary to perform rapid functional assays. The instrument must be capable of dispensing reagents into individual wells without removing the plate from the instrument required for accurately measuring calcium flux assays. The equipment will be used for COVID, malaria, and tuberculosis research, to identify potent monoclonal antibodies against these pathogens. Measuring this data during functional assays is essential for choosing the most potent antibodies against COVID, malaria, and tuberculosis.� The Agilent BioTek Synergy Neo2 Hybrid Multimode Microplate Reader is the only hybrid multimode reader that has a hybrid optical system combining an independent monochromator fluorescence optical system with an independent filter-based fluorescence optical system in the same instrument with multiple parallel detectors for ultra-fast simultaneous measurements in time sensitive assays. This instrument includes quadruple scientific grating optical design (two gratings per monochromator) for better spectral scanning performance compared to other monochromator designs, such as linear monochromators. The Neo2 also has continuously variable bandwidth monochromators for fluorescence measurements in 1 nm increments from 3nm to 50nm, allowing independent adjustments for excitation and emission windows and is capable of performing fluorescence and absorbance spectral scans. The plate reader also includes fiber-free filter-based optics for increased optical efficiency. The BioTek Synergy Neo2 Hybrid Multimode Microplate Reader is also designed for high-throughput functionality, with a maximum read speed of six seconds for 96-well plates and 11 seconds for 384-well plates, including for dual measurement fluorescence polarization assays and the option to add a plate stacker with plate exchange rates of six seconds. The Synergy Neo2 is capable of automatically dispensing reagents in all detection modes and is compatible with 2 �L low-volume microplate accessory with 16- or 48-sample microspots for direct nucleic acid quantification, as well as fluorescence and luminescence measurements. The instrument allows for highly controlled incubation parameters, including temperature control up to 70�C with a 4-zone temperature control system and the ability to set a temperature gradient to prevent condensation on plate lids. There is a maximum deviation of 0.5?C at 37?C across the plate. The BioTek Synergy Neo2 Hybrid Multimode Microplate Reader has top/bottom detector automatic focus adjustment to automatically accommodate for various microplate heights and fluid levels and automatic individual well-by-well absorbance path length correction to automatically calculate 1 cm path length corrected results and compensate for pipetting errors in microplates. The Biotek Synergy Neo2 multi-mode reader is capable of all of this functionality in a high throughput manner. The National Institute of Allergy and Infectious Diseases (NIAID) has a requirement for the following Brand Name Supplies: 1)�� �Agilent BioTek Synergy Neo2 Hybrid Multi-Mode Microplate Reader, Model� � � � NEO2SM, CAT # N2SM-SN 2) �To include: Monochromater: ABS, FI and LUM; Filter: Single filter top FI/FP/TRF� � � �and LUM, Detector Type: Photodiode; Fluorescence/Alpha: Dual PMT or Single� � � �PMT (option), Incubator. Temperature: +/-0.2?C at 37?C 3)�� �Agilent BioTek Filter Cubes for Synergy Neo2 Hybrid Multi-Mode Microplate Reader, GFP excitation/emission/luminescence filter cube, For Use With: Synergy Neo2 Hybrid Multi-Mode Microplate Reader, Imaging, Wavelength: Excitation: EX 485/20, Emission: EM 516/20, DM 510 4)�� �Agilent Dual Reagent Injector Module with two syringes, two reagent bottles, two bottle holders, and inlet tubing 5)�� �Agilent Dual Reagent Injector Module Accessories including feedthrough assembly with straight dispense tips 6)�� �Extended 2-year warranty for Neo2 Hybrid Plate Reader Place of Performance: NIH, NIAID, 5625 FISHERS LANE, ROCKVILLE, MD 20852, United States. �FOB: Destination The government intends to award a firm fixed price purchase order to the responsible contractor as a result of this RFQ that will include the terms and conditions set forth herein. �The award will be based on the following: technical capability to meet the requirements and price. The following FAR provisions apply to this acquisition:� FAR 52.212-1 Instructions to Offerors Commercial Items (MAR 2023) FAR 52.212-3 Offerors Representations and Certifications - Commercial Items (DEC 2022) FAR 52.204-7 System for Award Management (OCT 2018) (Offerors must complete annual representations and certifications on-line at http://www.sam.gov/ in accordance with FAR 52.212-3 Offerors Representations and Certifications- Commercial Items (Please ensure FAR 52.209-2 -- Prohibition on Contracting with Inverted Domestic Corporations--Representation. (Nov 2015) is updated in your SAM record) FAR 52.203-18 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements � Representation (JAN 2017) FAR 52.204�26 Covered Telecommunications Equipment or Services-Representation (OCT 2020) *** Must complete representation if attached to this solicitation- see attachment 52.204-26 The following FAR contract clauses apply to this acquisition: FAR 52-212-4 Contract Terms and Conditions Commercial Items (DEC 2022) FAR 52-212.5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items (JUNE 2023) *The applicable subparagraphs of FAR52.212-5 are included in the attachment to this posting. FAR 52.232-40 Providing Accelerated Payments to Small Business Subcontractors (MAR 2023) FAR 52.204-13 System for Award Management Maintenance (OCT 2018) FAR 52.204-25 Prohibition on Contracting for Certain Telecommunications and Video Surveillance Services or Equipment (NOV 2021) HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (DEC 2015) 52.252-2 -- Clauses Incorporated by Reference. (FEB 1998) This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address: �http://farsite.hill.af.mil/vffara.htm By submission of an offer, the offeror acknowledges the requirement that a prospective awardee shall be registered in the System for Award Management (SAM) database prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation (www.sam.gov). Copies of the above-referenced provisions and clauses are available from http://www.acquisition.gov/far/loadmainre.html & http: //www.hhs.gov/regulation/index.html or, upon request, either by telephone or fax. Submission shall be received not later than Friday, August 25, 2023 @ 4:00 PM EST Offers may be e-mailed to Diana Rohlman (E-Mail/diana.rohlman@nih.gov). Offers shall include RFQ number in the subject line (RFQ-NIAID-23-2174941). Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f).� All responsible sources may submit an offer that will be considered by this Agency. � Any questions or concerns regarding this solicitation should be forwarded in writing via e-mail to Diana Rohlman at diana.rohlman@nih.gov. �
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/0de025f2f3124a44b705a167edf140c9/view)
- Place of Performance
- Address: Rockville, MD 20852, USA
- Zip Code: 20852
- Country: USA
- Zip Code: 20852
- Record
- SN06793578-F 20230818/230817085754 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's SAM Daily Index Page |