Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF AUGUST 20, 2023 SAM #7936
MODIFICATION

66 -- Whole-Body Plethysmography System

Notice Date

8/18/2023 11:37:55 AM
 

Notice Type

Combined Synopsis/Solicitation
 

Contracting Office

NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
 

ZIP Code

20892
 

Solicitation Number

75N95023Q00416
 

Response Due

8/25/2023 9:00:00 AM
 

Archive Date

08/25/2023
 

Point of Contact

Scott Duernberger, Phone: 3015940670, Josh Lazarus, Phone: 3018276923
 

E-Mail Address

scott.duernberger@nih.gov, josh.lazarus@nih.gov
(scott.duernberger@nih.gov, josh.lazarus@nih.gov)
 

Description

This is a request to expand our whole body plethysmography system. The system will allow NIDA to study the causes of opioid overdose deaths by comparing the effects of currently approved drugs to treat opioid dependence on opioid-induced overdose deaths and studying the potential effects of novel compounds in reversing opioid-induced respiratory depression. The Neurobiology of Additiction Section (NOAS) of the Integrative Neuroscience Research Branch (INRB), National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) seeks to to understand how cellular and molecular changes produce changes in particular neurocircuits to convey negative emotional states that contribute to the motivation to seek drugs. The NOAS is examining drug dependence as a complex psychiatric condition characterized by craving, compulsive drug seeking, excessive drug taking, and the emergence of negative emotional states during withdrawal. With the opioid epidemic recently declared a public health emergency due to the unprecedented high levels of opioid-related overdose deaths, NAS is working to test currently approved medications for opioid dependence. There are medications approved for the treatment of opioid addiction. However, it is unknown whether these medications protect or make it worse if an individual relapses to drug taking. In order to examine these effects, a whole-body plethysmography system is required to currently approved medications for opioid dependence as well as novel medications for their potential to block or reverse respiratory depression caused by opioids.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/170c0677878b4083b13ef1c66c43c172/view)
 

Place of Performance

Address: Baltimore, MD 21224, USA

Zip Code: 21224

Country: USA
 

Record

SN06796664-F 20230820/230818230052 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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