SOURCES SOUGHT
66 -- Next-Generation Sequencing (NGS) Liquid Handling Systems
- Notice Date
- 7/18/2024 2:02:50 PM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIAID BETHESDA MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- SS-NIAID-24-2227841
- Response Due
- 8/5/2024 12:00:00 PM
- Archive Date
- 08/20/2024
- Point of Contact
- Daveta H. Brown, Linda Smith
- E-Mail Address
-
daveta.brown@nih.gov, linda.smith2@nih.gov
(daveta.brown@nih.gov, linda.smith2@nih.gov)
- Description
- Introduction This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. Project Summary The National Institute of Allergy and Infectious Diseases (NIAID), Genomic Analysis Core (GAC), Vaccine Research Center (VRC), is seeking to acquire two (2) liquid handling systems.� The GAC/VRC focuses on the understanding of immunogenicity and antibody repertoires elicited by candidate immunogens for many endemic and emerging infectious diseases.� This research endeavors aid in the GAC�s/VRC�s ability to design, produce, and test candidate immunogens aimed at eliciting neutralizing antibodies against several human pathogens, and more specifically, for pandemic preparedness. The liquid handler systems are required for single cell-based antibody discovery crucial for pandemic preparedness efforts related to emerging arboviruses. These liquid handlers are also required for RNA and DNA processing, NGS applications, and antibody expression/production. These instruments allow multiple members of the lab to process samples in a high-throughput manner to contribute to the VRC's efforts in vaccine and therapeutics development. These types of instruments are needed to fulfill this requirement.��� Specifically, NIAID, GAC, VRC is seeking two instruments capable of the following: 1. Liquid handling systems a. Dispensing system: the system must use liquid dispensers with TRUE positive displacement of liquids for aspiration and non-contact dispensing with 6 dispensing syringes. b. Pipetting system: the system must include at least a 384 tips air-displacement pipetting head, working in a minimum range from 0.5uL to 125uL.� Plastic consumable tips must be automatically exchanged by the system and available in 384, 96, 8, and 16 channel arrays, for flexibility to work with a wide variety of 96 and 384 well plates.� The system must be able to automatically switch between these formats for flexibility. c. Expansion kit that includes a ring magnet, 96 well built in thermocycler and alternate head. 2.�Liquid Class management a.�Dispenser Liquid classes: the dispense system must be capable of handling a wide range liquid type from 80% ethanol through to 50% (w/v) glycerol, with NO requirement for liquid classification.� Common biological assay components such as aqueous buffers, DMSO, beads, cells, or glycerol protein stocks must all be dispensed using the same standard settings as well as particulates such as SPRI beads.� b.�Pipetting liquid classes: The pipetting system must use liquid classes to compensate for different liquid types and is well suited to a range of liquid types.� It uses an air-displacement pipetting system. 3. NIAID has limited space and requires a small footprint 26 inches wide by 22 inches deep. 4. User Interface must be completely configurable to tailor the user experience from those requiring restricted access to run specific protocols only, to full open access to all features for Super users.� Must be able to install the software on any windows device to author protocols virtually anywhere and send them to the system via a network or over the cloud. 5. The system must include fixed base configurations to share protocols between systems.� Configuration must also include a microplate shaker and incubation capabilities. 6. Must be application ready with off the shelf protocols ready to use. Anticipated Period of Performance It is anticipated that an award will be made on or around September 20, 2024. �Estimated lead time for delivery of instruments is 60-120 days upon Vendor�s receipt of the purchase order. Capability Statement/Information Sought If your organization has the potential capacity to meet the minimum requirements and performance capabilities listed above, please provide the following information: Organization name, address, point of contact, email address, website address, telephone number, UEI number. Company location(s) and number of years company has been in business. Type of business (e.g., 8(a), HUBZone, Other than Small, etc.) �pursuant to the applicable NAICS code. Type of ownership for the organization. Identification of any Best-In-Class contract vehicles including Government Wide Acquisition Contracts (GWAC) (e.g., GSA schedule) they may possess or are aware of that would support this possible requirement. If your organization does not provide the products/services under a GWAC, please identify availability as OPEN MARKET ONLY. Tailored capability statement addressing the capability of the liquid handling systems to meet NIAID�s minimum requirements. Capability document shall be no more than six pages. Place of manufacture for the liquid handling systems and components. Evidence that the organization is an authorized reseller or manufacturer of the instrument. Only Original Equipment Manufacturer (OEM) products are acceptable. � Please provide information on the sustainability of the equipment and any associate parts.� Are any parts of the system energy efficient consistent with ENERGY STAR certified or FEMP-designated products?� Furthermore, are there any sustainability practices used in manufacturing the instrument system such as use of recovered materials, biobased products, or alternatives to ozone-depleting substances? Submission Instructions Interested businesses who consider themselves qualified to provide the above specification for the Liquid Handling Systems, are invited to submit a response to this Sources Sought Notice by August 5, 2025, at 3:00 PM EST. All responses under this Sources Sought Notice shall be emailed to Daveta H. Brown at daveta.brown@nih.gov. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in Federal Business Opportunities. �However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/4c0ad22d12e4437287f7343ee00125ee/view)
- Place of Performance
- Address: Bethesda, MD 20814, USA
- Zip Code: 20814
- Country: USA
- Zip Code: 20814
- Record
- SN07135301-F 20240720/240718230125 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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