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SAMDAILY.US - ISSUE OF FEBRUARY 08, 2026 SAM #8840
AWARD

66 -- Screen the A10 antibody for off-target binding to plasma membrane proteins and secreted proteins

Notice Date
2/6/2026 7:02:20 AM
 
Notice Type
Award Notice
 
NAICS
541380 — Testing Laboratories
 
Contracting Office
PROGRAM SUPPORT CENTER ACQ MGMT SVC ROCKVILLE MD 20857 USA
 
ZIP Code
20857
 
Solicitation Number
75N91026P00004
 
Archive Date
02/11/2026
 
Point of Contact
Elizabeth Bulger
 
E-Mail Address
elizabeth.bulger@hhs.gov
(elizabeth.bulger@hhs.gov)
 
Small Business Set-Aside
NONE No Set aside used
 
Award Number
75N91026P00004
 
Award Date
01/27/2026
 
Awardee
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED Saffron Walden CB10 1XL GBR
 
Award Amount
38750.00
 
Description
This is a Firm Fixed Priced purchase order. NCI solicited and negotiated directly with Charles River Discovery Research Services UK Limited. The National Cancer Institute (NCI) has a program to use an antibody called, 'A10' to target cancer cells that have a lot of the epidermal growth factor receptor on their cell surface. While this antibody has been extensively tested and characterized it is not known if it also binds any other cell surface proteins. The contractor shall perform an off-target screen on an NCI antibody and report back on any problematic interactions that could predict a serious side effect should the antibody be given to a cancer patient. The A10 is NOT known to bind other cell surface proteins or secreted proteins but this needs to be addressed in the off-target screen.
 
Web Link
SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/1f593f2d0a2a4dc6b1e87d1efe846498/view)
 
Place of Performance
Address: Saffron , GB-ESS, GBR
Country: GBR
 
Record
SN07707131-F 20260208/260206230038 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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