SOLICITATION NOTICE
A -- Critical Illness Immunological Reprogramming and Control Point Learning Engine (CIRCLE) Innovative Solutions Opening (ISO)
- Notice Date
- 2/17/2026 9:50:22 AM
- Notice Type
- Solicitation
- NAICS
- 541715
— Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Contracting Office
- ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) Washington DC 20005 USA
- ZIP Code
- 20005
- Solicitation Number
- ARPA-H-SOL-26-139
- Response Due
- 5/29/2026 10:00:00 AM
- Archive Date
- 06/13/2026
- Point of Contact
- ARPA-H RSO CIRCLE ISO Coordinator
- E-Mail Address
-
CIRCLE@ARPA-H.gov
(CIRCLE@ARPA-H.gov)
- Small Business Set-Aside
- NONE No Set aside used
- Description
- The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) solicitation in support of the Critical Illness Immunological Reprogramming and Control Point Learning Engine (CIRCLE) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement. CIRCLE seeks to create a critical illness Control Point Validation Engine that leads to improvements in intensive care unit (ICU) health outcomes, coupled to reduced stay time and associated costs, by assessing, predicting, and treating immuno-inflammatory dysregulation before it causes organ failure. Interested parties are invited to review the attached CIRCLE ISO ARPA-H-SOL-26-139 and its Attachments A � F. Proposer's Day: Wednesday, March 11, 2026 (ARPA-H-SN-26-149) Solution Summaries Due: Monday, March 30, 2026, 1 PM ET (to https://solutions.arpa-h.gov) Questions Due: Friday, May 22, 2026, 1 PM ET (to https://solutions.arpa-h.gov/Ask-A-Question/) Full Proposals Due: Friday, May 29, 2026, 1 PM ET (to https://solutions.arpa-h.gov) ARPA-H will not reimburse potential proposers for time and effort related to submission of solution summaries or proposals. When planning a response to this notice, proposers should consider that some parts of the submission process may take from one business day to one month to complete.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/a890cc996d3946678fdf92306c58f328/view)
- Place of Performance
- Address: USA
- Country: USA
- Country: USA
- Record
- SN07717341-F 20260219/260217230040 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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