Office of Naval Research, 800 North Quincy Street Arlington, VA 22217-5660

A -- CELL ADHESION MOLECULE RESEARCH OPPORTUNITIES POC Point of Contact: D. VanMetre, ONR 251B (703) 696-4525. The Office of Naval Research is initiating a short-term research program on cell adhesion molecules in order to better understand the role of these molecules in inflammatory reactions such as allergic rhinitis and atopic allergic conditions. In accordance with Congressional language, this research should be performed by an integrated team of scientists affiliated with a non-profit foundation in the northeast (north of Virginia, west to Ohio) with extensive experience in the molecular analysis of the immune system. In particular, the scientific team must have extensive experience in the identification and analysis of cell adhesion factors, signal transduction pathways, cytokine production and gene regulation. This is a Broad Agency Announcement. There is no request for proposal nor any other formal application document. It is not the intent of this program to establish new facilities, rather, non-profit foundations in the appropriate geographic area having demonstrated research capability and appropriate facilities are invited to submit three copies of a preproposal not exceeding three pages of text that describes: a) the research objective, b) the proposed research approach, c) related work by the proposer, d) the anticipated contribution to the Office of Naval Research program, e) an estimate of overall costs (including indirect) for a 1 to 1.5-year effort. Direct costs may include capital equipment. A curriculum vitae of the principal investigator(s) should be appended together with any supporting information, such as reprints or preprints, that assists in the evaluation of the preproposal. Preproposal submissions will be evaluated on the basis of innovativeness, focus, and integrated team strengths. Full formal proposals for competitive review will be requested based on those submissions judged most relevant to the program objectives, proposal deadline dates and format instructions will be provided at that time. The deadline for preproposals is 7 February 1995. Technical questions should be directed and preproposals should be sent to: Dr. Constance Oliver, ONR 341, Office of Naval Research, 800 N. Quincy St., RM 823, Arlington, VA 22217-5660, Phone (703) 696-4053, Fax (703) 696-1212. (0004)

Loren Data Corp. http://www.ld.com (SYN# 0006 19950105\A-0006.SOL)