National Institutes of Health, Division of Procurement, AB-D 6120 Executive Blvd., Eighth Floor, Rockville, MD 20892 ATTN: Julius Y. Tidwell

70 -- ADP SOFTWARE PROGRAMS AND SUPPORT SERVICES SOL 263-94-P(DG)-0633 DUE 061194 POC Julius Y. Tidwell, (301) 402-3074; Contracting Officer, Marian B. Louden, (301) 496-3660. The National Institutes of Health, DHHS intends to negotiate on a sole source basis Skylight Software Incorporated, 323 Andover Street, Wilmington, MA 01887 for the development and acquisition of various software programs and ADP Support Services. The Government anticipates awarding a contract for a twelve month base period and the contract shall contain four twelve month option periods for the acquisition of support services. The Contractor shall develop and deliver 1. Software for multi-channel voltage signal processing and visualisation, to include data adjustments, fitting, profile building, and transformations; 2. Develop and deliver software for complicated voltage signals generation and acquisition allowing users to choose different computer interfaces to plot acquired data and to produce the composition of sine waves, ramps, square signals, and synchroimpulses; 3. Develop and deliver software for membrane current spectra analysis, storage, and processing allowing the performance of on-line calculations and plotting of basic electrical values; 4. Develop and deliver mathematical models and algorithms for the calculation of fusing-cell electrical parameters, including the selection of input channels and parameter-fitting; 5. Develop and deliver software for the determination of fusion pore conductance and fusing cells' conductances and capacitances, to be intergrated with software currently being used for the evaluation of dye spreading in optical images of fusing cells; 6. Develop and deliver a user friendly menu-driven graphical user interface based on Microsoft Windows Operating System. The developed software will be combined with optical image processing software packages owned and customized by the Government. The Government anticipates using the services of a professional systems programmer/analyst with an advanced degree in mathematics and whom has experience in manipulating and presenting statical data. The programmer/analyst must have programmer/analyst must have programming experience in Microsoft C++, C, Visual C++, Fortran, Assembler, MS Windows and UNIX. The programmer/analyst must also have experience in programming control programs; developing software for PC based signal generation and analysis; and troubleshooting software drivers for A/D and D/A interfaces on Personal Computers. The programmer/analyst shall also have experience with local area networks and using and refining digital signal processing algorithms. Interested firms capable of performing the required services to provide the requested software and technical support services similar to those described above are encouraged to respond. All responses must be written and received within 45 calendar days from the published date of this notice. Oral communication is not acceptable and will not be honored. Responding firms with expertise should submit their professional qualifications with a detailed description of any similar completed or ongoing efforts. All responses should be brief and concise. No elaborate proposal is requested. Interested firms are requested to specify whether they are a small or large business concern in accordance with Standared Industrial Code 7371, and a size standared of 7.0 million dollars. Responses requesting the solicitation without the required documentation shall not be considered. There is no solicitation document. See Note 22. (0009)

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