Centers for Disease Control and Prevention, Procurement and Grants Office, 255 East Paces Ferry Road NE, Room 507, Atlanta, Georgia 30305

B -- EPIDEMIOLOGICAL STUDY OF THE ASSOCIATION BETWEEN FOLATE INTAKE AND THE CLINICAL MANIFESTATION OF VITAMIN B12 DEFICIENCY SOL 200-95-0908(P) DUE 041495 POC Contact Valree S. Chambers at (404) 842-6719 The Centers for Disease Control and Prevention contemplates awarding a contract to design and conduct a case-control study of the effect of total dietary folate intake on the clinical presentation of Vitamin B12 deficiency. The successful offeror shall develop case definitions, devise a mechanism for identifying cases and selecting controls, develop dietary assessment instruments, and develop a plan for rapid, prospective interviewing of cases and control. A database with hematologic, clinical, dietary, and sociodemographic data on cases and controls shall be delivered to the Government. The following criteria MUST be met in order to be considered for award under this solicitation: (1) Offeror must provide documentation which demonstrates participant enrollment of two million or more, (2) At least 25 percent of the enrolled participants must be 50 years old or older, and (3) The offeror must document an average of 1000 incident cases of Vitamin B12 deficiency per calendar year. NOTE: A specialized center receiving referrals for diagnosis or retirement will NOT be considered, since the patient population is not representative of the underlying population of at-risk individuals. The scheduled issue date is approximately February 28, 1994. NO TELEPHONE REQUESTS WILL BE ACCEPTED; only written requests for this solicitation will be honored. Fax requests will be honored; send fax documents to (404) 842-6727. Written requests should cite RFP No. 200-95-0908(P). All responsible sources that meet the above requirements may submit a proposal which shall be considered by the Agency. (0018)

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