National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, EPS/620, 6120 EXECUTIVE BLVD MSC 7224, BETHESDA MD 20892-7224

A -- CONTINUATION OF FOLLOW-UP ON PARTICIPANTS IN THE BREAST CANCER DETECTION DEMONSTRATION PROJECT (BCDDP) SOL NCI-CP-50532-02 DUE 030895 POC Michael J. Loewe Contract Specialist (301) 496-8611. The National Cancer Institute (NCI) is re-competing a contract for Continuation of Follow-up on Participants in the Breast Cancer Detection Demonstration Project (BCDDP). This requirement is a recompetition of contract No. N01-CP-21008 with Westat, Incorporated. The study will be based on a sample of 64,185 of the 280,000 women who previously participated in a five-year multi- center breast cancer screening program -- the BCDDP -- conducted during 1973-1980. Under this proposed acquisition, the contractor shall conduct further follow-up on a cohort consisting of the approximately 53,000 remaining women from the original cohort of 64,185. The average age of the cohort at the time of the continuation of the study will be approximately 68 years. The study is expected to last three years. The Contractor shall establish and maintain a centralized office in which documents associated with this study can be stored and from which mail and telephone interviews can be conducted. The Contractor shall modify existing mail and telephone questionnaires. The Contractor shall provide personnel to conduct the follow-up activities, obtaining the following information for each participant: (1) vital status information on cohort members, (2) responses to one mailed questionnaire from living study subjects during the three-year study period, (3) copies of pathology reports, hospital discharge summaries and operative reports for all cancers and breast procedures reported since the last interview performed during the period September 30, 1992 through September 29, 1995, (4) copies of estrogen and progesterone receptor reports for all breast cancers reported since the last interview and (5) copies of death certificates for all deceased subjects since the last interview. The estimated total level-of-effort for the three-year period of performance is 44,000 direct labor hours. It is anticipated that the RFP package will be available on or about February 6, 1995 with responses due within 30 calendar days following the actual date of issuance of the RFP. Award of this project is anticipated by September 30, 1995. All responsible sources may submit a proposal which shall be considered by the NCI. No collect calls will be accepted. (0019)

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