National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, EPS/620, 6120 EXECUTIVE BOULEVARD MSC 7224 BETHESDA MD 20892-7224

A -- SUPPORT SERVICES FOR GENETIC EPIDEMIOLOGIC STUDIES SOL NCI-CP-50534-02 DUE 031595 POC Michael J. Loewe Contract Specialist (301) 496-8611. The Genetic Epidemiology Branch (GEB) of the National Cancer Institute (NCI) is re-competing a contract for Support Services for Genetic Epidemiologic Studies. This requirement is a combined recompetition of the requirements of contract Nos. N01-CP-15602 (Support Services for Clinical Epidemiologic Studies) with Survey Research Associates, Incorporated and N01-CP-15672 (Support Services for Epidemiologic Studies) with Westat, Incorporated. The contract will establish a mechanism to provide all the support services required to conduct a wide variety of domestic and international family studies and field studies. While the scientific direction and overall supervision for all projects are the responsibility of the professional staff of the GEB, the Contractor will provide or perform the following: 1) nursing support including contacting family members, explaining the studies, enrolling family members, obtaining clinical information and records, arranging for family members to be evaluated by GEB investigators in the Cancer Genetics Clinic at the Clinical Center, performing phlebotomy, obtaining other biologic specimens as needed, arranging and conducting field trips to evaluate family members, and developing and providing educational materials for participants, 2) maintenance of a locked medical record room to which GEB investigators could have immediate access, 3) development of coordination and liaison at a local or international level with collaborating investigators or institutions whose cooperation is needed for the conduct of a study, 4) assistance in the design and pilot testing of forms required for field investigations (e.g., questionnaires, abstracting forms, coding forms, manuals for field procedures and other documents), 5) hiring, training and supervision of field personnel (interviewers, abstractors, and others), 6) identification of study subjects, including locating cancer patients and/or their relatives, selection of controls through such methods as random digit dialing and acquisition of appropriate study population rosters or files, 7) supervision and management of field operations, 8) collection of data (interviewing/record abstraction, biologic specimen collection and processing), 9) data reduction activities (coding, keying, and editing) of data collected into a format suitable for computer analysis, 10) quality control and standardization so that appropriate and valid data result. The maintenance of a secure record room which allows GEB investigators access to the medical records within 15 minutes is a mandatory requirement. It is anticipated that the Request for Proposal (RFP) package will be available on or about February 13, 1995 with responses due within 30 calendar days following the actual date of issuance of the RFP. Award of this project is anticipated by September 30, 1995. All responsible sources may submit a proposal which shall be considered by the NCI. No collect calls will be accepted. (0027)

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