Department of Health and Human Services, National Institute on Drug Abuse, Contracts Management Branch, OPRM, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, Maryland 20857

A -- CPDD ANTINOCICEPTION, PHYSICAL DEPENDENCE AND ABUSE LIABILITY TESTING SOL N01DA-5-8059 DUE 051595 POC Contact Point: Jeffrey Weiner, Contract Specialist (301) 443-6677; Nancy A. Hurd, Contracting Officer The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having in-house capability to: evaluate the antinociceptive activity of test compounds in mice; evaluate the effects of test compounds in opiate dependent rats and rhesus monkeys; evaluate the intrinsic physical dependence capacity of test compounds in drug-naive rhesus monkeys; and assess the reinforcing properties of test compounds in rhesus monkey self-administration studies. The offeror must also indicate possession of current DEA registration for Schedule II-V substances prior to award and apply for Schedule I registration for heroin and, if applicable, other Schedule I substances. Estimated issuance date of RFP No. N01DA-5-8059 is March 14, 1995 and responses are due to be received in the Contracting Office 60 calendar days thereafter. Written requests for copies of solicitations will be honored if received within twenty calendar days after issuance of the solicitation. Written requests received after this period will be filled on a first-come, first-served basis until the supply is exhausted; however, there is no assurance that copies requested after the twentieth day will reach the requestor before the due date for receipt of responses. The Government reserves the right to make more than one award or no award at all in response to this RFP. Moreover, the RFP may be amended or canceled if determined to be in the best interest of the Government. Written requests shall be forwarded to the attention of Contract Specialist, Jeffrey Weiner, National Institute on Drug Abuse, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, Maryland 20857. (0039)

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