National Institutes of health, Division of Procurement, AB-A 6120 Executive Blvd., EPS/800, Rockville, MD 20892

66 -- MASS SPECTROMETER SYSTEM SOL 263-95-P-(GD)-0025 POC Donald Wilson, Contract Specialist, 301-402-2849. 17. The National Institutes of Health intends to negotiate with Hewlett Packard, P.O. Box 7777-W8770, Philadelphia, PA 19175 as a sole source under the authority of 41. U.S.C. 253(c)(1), for a Mass Spectrometer, Maldi-tof System Bundel model number G2025A (install), including an Oscilloscope model number LECR-9350M. The Mass Spectrometer System shall be as manufactured in accordance with the functional/performance characteristics herein as follows: The mass spectrometer shall have a mass accuracy of at least + 0.3% for a protein of 50,000 mass units when using external standards. The reproducibility of such proteins shall be better than + 0.1%. The mass spectrometer shall provide a mass detection range which shall extend to at least 300,000 mass units for proteins. Shall provide from 50,000 to 300,000 mass unit sensitivity. The mass spectrometer shall be capable of detecting low molecular weight molecules such as dipeptides in a matrix containing salts and buffers such as Tris. The mass spectrometer shall be capable of full operation and calibration in the positive and negative ion modes. Switching from one mode to the other shall be under software control to allow for unattended automated runs. The mass spectrometer shall provide for sample deposition resulting in even distribution across the probe surface. Automatic operation shall include the ability to scan at least 25 discrete regions of each sample target and then select the optimum region for data accumulation according to criteria applied laser power and of signal to noise ratio in the spectrum. The mass spectrometer shall have the ability for suppression of matrix ions. The mass spectrometer shall have a sensitivity signal to noise ratio of at least 100 for 50 femtomoles of a peptide of about 6,00 mass units. It is the Government's belief that these requirements can be met by Hewlett Packard. This is not a formal solicitation. However, concerns that respond to this notice must furnish concise responses directed specifically to the requirements mentioned above. Sources demonstrating the capability to accomplish the above shall supply pertinent information in sufficient detail to demonstrate that ability to perform. Information furnished shall include enough material to perform a proper evaluation. Respondents will not be notified of the evaluation results. See note 22: (0059)

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