U.S. ARMY MED. RESEARCH ACQUISITION ACT, MCMR-RMA-IC, FORT DETRICK BLDG. 820, FREDERICK MD 21702-5014

A -- DEVELOPMENT OF ORAL MICROENCAPSULATED VACCINE, PILE BASED AGAINST ENTERTOXIGENIC E. COLI AND MICROENCAPSULATED ANTIBIOTICS AND ANESTHETICS. SOL DAMD17-95-R-5029 DUE 051595 POC Monica J. Pileggi, Contract Specialist, (301) 619-2377;, George J. Bauman, Jr., Contracting, Officer (301) 619-2369 The Division of Medicine at the Walter Reed Armed Institute of Research (WRAIR) seeks one individual to provide consultative services and technical assistance relevant to the development of a microencapsulated adherence- factor based oral vaccine against ETEC, the expansion of the microencapsulation technology base for in-house applications and support for the technology transfer of developed products for dual use. The Government intends to solicit and negotiate with only one source under the authority of FAR 6.302-1. The purpose of this sources sought synopsis is to conduct a market survey to determine the existence of other sources. We plan to contract with Dr. Robert H. Reid of Kensington, MD by other than full and open competition to supply services available from only one source. A one year contract is anticipated. Individuals who believe they can perform this requirement may submit a capability statement and must have the following qualifications: a) A physician trained in Internal Medicine/Allergy and Clinical Immunology with experience in GMP, IND, clinical protocols and clinical studies; b) Have in-depth knowledge and experience in CFA-based vaccine development against ETEC, and a full awareness of work previously accomplished in the Gastroenterology Department; c) Have extensive experience in microencapsulation technology and in the functioning of the Army's microencapsulation facility; d) Have knowledge of existing CRADAs, companies interested and/or participating in microencapsulation technologies and potential for collaborations conducive for the transfer of the microencapsulation technology; e) Have knowledge of the capabilities within the Department of the Gastroenterology, microencapsulation facility, DRD and GMP facility (Bldg 501); f) Have knowledge of computer based moecular model of MHC II DRI. Capability statements received will be evaluated solely for the purpose of determining whether to conduct a competitive procurement. The above stated information must be submitted in writing (original and one copy) within fifteen (15) days after publication of this notice to U.S. Army Medical Research Acquisition Activity, ATTN: MCMR-RMA-IC, (Monica Pileggi), Fort Detrick, Frederick, MD 21702-5014.(0095)

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