National Institutes of Health, Office of Purchasing and Contracts, CC 6006 Executive Blvd., Suite 311, Bethesda, MD 20892-7058

66 -- AUTOMATED SYNETHESIS UNIT FOR ''C METHYLATION SOL CC-95-06 POC Ann Argaman, Contract Specialist, or Patrick Williams, Contracting Officer (301)496-3704. THIS IS A NOTICE OF INTENT THAT THE NATIONAL INSTITUTES OF HEALTH UNDER THE AUTHORITY OF 41 USC 253 (C) (1) intends to negotiate and award a sole source contract to Nuclear Interface to provide an automated synethesis unit for (''C) methylation. Nuclear Interface is the only known firm with the capability and expertise to provide the automated synethesis unit for (''C) methylation. The following requirements are mandatory for the new automated system: It must be a closed system with the capability of being sterilized. The emission of radioactivity must be as low as reasonably acceptable. Ideally, all gaseous material will be trapped within the system and allowed to decay. The system must be compact, that is, it must be no larger than 1.5 ft in each dimension. The synethesis unit must be computer controlled and operate fully automatic. The synethesis should be displayed graphically along with key parameters. An automatic cleaning and purging procedure must be included. All valves must be able to be controlled manually. Important parameters such as temperature, pressure, and radioactivity must be recorded, displayed graphically, and stored permanently. There should be the possibility for an integrated chromatography system. The synthesis sequence program should be able to be modified by the user. All responses must be written and received within 45 calendar days from the published date of this notice. Oral communication is not acceptable and will not be honored. A Statement of Work is available upon request. Responses requesting the solicitation without providing the required documentation shall not be considered. There is no solicitation document. Concerns that respond to this notice will be considered only if furnishing clear and convicing documentation demonstrating their ability to meet, at a minimum the stated requirements. Written responses should contain sufficient technical information and a description of the proposed system to be supplied which meets the requirements, in order to permit agency analysis to establish a bonafide capability to meet tha stated requirements and should be directed to Ann Argaman at the address above. A determination by the Government to open the requirement to competition based upon responses to this notice is solely within the discretion of the Government. The Government will not pay for preparation or submission of any information submitted in responses to this synopsis. See Numbered Note(s): 22. (0104)

Loren Data Corp. http://www.ld.com (SYN# 0257 19950417\66-0001.SOL)