Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Contracts Management Branch, OPRM, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, MD 20857

A -- SYNTHESIS AND DISTRIBUTION OF DRUGS OF ABUSE AND RELATED COMPOUNDS SOL NO1DA-6-7054 DUE 101695 POC Carol A. Cushing, Contract Specialist, (301) 443-1301, Nikki A. Zangwill, Contracting Officer, (301) 443-1301 The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having the experience and ability to synthesize authentic and standardized research compounds including both unlabeled compounds and compounds labeled with deuterium, tritium, carbon-14, and iodine-125 isotopes. The types of compounds to be synthesized include cannabinoids, unnatural opiates, narcotics, stimulants, depressants, hallucinogens, opiate antagonists, receptor ligands, designer drugs, cocaine and cocaine metabolites and related compounds. NIDA Drug Supply Program has played a major role in these contributions by providing to the drug abuse research cpmmunity a wide variety of authentic and standardized research compounds, and this contract is to assure the supply of a large number of ultrapure compounds that are thoroughly characterized and that the service to the research community is unterrupted. The Offeror must possess the necessary expertise, laboratory space, instrumentation, and experience in the synthesis, purification, storage and distribution of these compounds. Offerors must submit, with the proposal, evidence of application or possession of a Drug Enforcement Administration Researcher Registration for Schedules I and II controlled substances, as well as the capacity to obtain an DEA Schedule I and II manufacturing, importer/exporter and distributor's registration by the time of award. It is estimated that a five- year incrementally funded cost-reimbursement type (completion) contract will be awarded with five additional one-year option periods. This is a follow on procurement to contract NO1DA- 1-7311 with Research Triangle Institute. Estimated issuance date of RFP No. NO1DA-6-7054 is August 31, 1995, and responses are due to be received in the Contracting Office 45 calendar days thereafter. Written requests for copies of solicitations will be honored if received within 35 calendar days after issuance of the solicitation. Requests received after this period will be filled on a first-come, first-served basis until the supply is exhausted. However, there is no assurance that copies requested after the 35th day will reach the requestor before the due date for receipt of responses. Only written or facsimile requests for this RFP will be accepted. Please forward all requests to the attentionof Ms. Carol Cushing, Contract Specialist, National Institute on Drug Abuse, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, Maryland 20857 (telefax number is 1-301-443-7595). (0222)

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