Asthma and Allergy Foundation of America, 1125 15th Street, NW, Suite 502, Washington, DC 20005

A -- CELL ADHESION MOLECULES RESEARCH OPPORTUNITIES Due 112295. POC Grant Administrator, Wilma Fields, (202) 466-7643. The Asthma and Allergy Foundation of America is initiating a short-term research program on cell adhesion molecules in order to better understand the role of these molecules in inflammatory reactions such as allergic rhinitis and atopic allergic conditions. This research must be performed by an integrated team of scientists affiliated with a non-profit institute in the northeast (north of Virginia, west to Ohio) with extensive experience in the molecular analysis of the immune system. In particular, the scientific team should have extensive experience in the identification and analysis of cell adhesion factors, signal transduction pathways, cytokine production and/or gene regulation. It is not the intent of this program to establish new facilities: rather, investigators in the appropriate geographic area having demonstrated research capability and appropriate facilities are invited to submit a proposal that describes: a) the research objective; b) the proposed research approach; c) related work by the proposer; d) the anticipated contribution to the asthma and allergy patient population; e) an estimate of overall costs (including indirect) for a one to three year effort. Direct costs may include capital equipment. The format instructions for the proposal may be obtained from the Asthma and Allergy Foundation of America (address below). Proposal submissions will be evaluated on the basis of relevancy of subject matter, innovativeness, focus, and integrated team strength. Technical questions and proposals should be sent to: Mary E. Worstell, Executive Director, Asthma and Allergy Foundation of America, 1125 Fifteenth Street NW, Suite 502, Washington, DC 20005, Phone (202) 466-7643; FAX (202) 466-8940. (289)

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