NIH, OPM, 6120 Executive Blvd, Rockville, MD 20892-7260

A -- DATA COLLECTION ON PERSONALITY AND PERSONALITY DISORDERS SOL 263-96-Q-0215 POC Kathleen Gleason, Purchasing Agent, 301/402-3346. This is a Notice of Intent announcing that the National Institute of Aging (NIA), National Institutes of Health (NIH), in Bethesda, Maryland intends to place an order with Hunan Medical University, Clinical Psychological Research Center, Hunan, People's Republic of China, to review medical records on personality & personality disorders in psychiatric hospitals & clinica in the People's Republic of China (PRC) and identify 1800 patients able and willing to respond to questionnaires and interviews. The Contractor shall perform the following specific duties: 1. Translate and Pilot Instruments: The contractor shall translate research instruments into Chinese or adapt existing translations for use in People's Republic of China. Instruments shall be pilot tested for accuracy and understandability, and a two (2) week test-retest reliability study shall be conducted on a subsample of fifty (50) psychiatric patients. The NIH will pay one-quarter of the amount of this requirement upon completion of this task. 2. Organize and Train Investigative Teams: The contractor shall invite psychaitrists and psychologists from several Centers of the Hunan Medical University to participate. Both (psychiatrists and psychologists) shall be trained in the use of questionnaires and interviews for the diagnosis of personality disorders. The contractor shall organize a committee to oversee the project and to protect patients' rights. 3. Administer Self-Report Questionnaires: On the basis of medical records, 1,800 patients and 200 of their spouses shall be recruited to participate. Subjects shall be administered the revised NEO Personality Inventory (NEO-PI-R) and the Personality Diagnostic Questionnaire (PDQ-4+). Spouses (N = 200) shall also provide ratings of the patients' personalities on the NEO-PI-R. 4. Conduct Psychiatric Interviews: Trained clinical psychologists or psychiatrists shall conduct two (2) interviews, the Hamilton Depression Rating Scale and the Personality Disorder Interview IV (PDI-IV), on a subset of seven hundred (700) patients. Of these, fifty (50) shall be interviewed independently by a second interviewer to assess interrater reliability, and fifty (50) shall be interviewed a second time after three (3) months to determine retest reliability. 5. Abstract and Enter Data: The contractor shall merge background and diagnostic data obtained from medical records with questionnaire and interview data, and shall enter on a computer file. Data entry shall be verified. The contractor shall provide complete documentation on the file, along with the data, to The Laboratory of Personality & Cognition, NIA, NIH. The balance payment of this requirement will be payable upon the completion of this task. 6. Concerns that respond to this notice shall furnish concise responses directer specifically to the requirements mentioned above. Sources demonstrating the capability to accomplish the above shall supply pertinent information in sufficient detail to demonstrate their ability to perform. 7. Written responses shall also include complete pricing information and a complete description of the services to be provided, containing sufficient technical information to permit agency analysis to establish a bona fide capability to meet the stated requirements as listed above. 8. Adequate detailed data by which to evaluate capability should be sent to Attn: Mrs. Kathleen Gleason, National Institutes of Health, 6120 Executive Blvd., Room 876, Rockville, Maryland 20852, Phone #301/402-3346. All responses from responsible sources will be fully considered. Please respond no later than the close of business 15 days after date published in the CBD. (0087)

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