CONTROLLED RELEASE OF EXPANDING DENDRIMERS Sandia National Laboratories is seeking partners to develop and commercialize a proprietary dendrimer technology. According to a recent Wall Street Journal (2/26/96) article, dendrimers have enormous market potential for applications in areas such as cosmetics, perfumes, deodorants, shampoo, time-released pharmaceuticals, in-vivo therapeutics and diagnostics, computer storage, electronics, and many other industrial and consumer products. The WSJ article stated that the market potential for these man made molecules with the hollow, 3-D structure, known as dendrimers, is enormous: ``a kilogram of dendrimers can generate $50 million in revenues.'' Of course, no one can predict whether our particular technology will be able to capture a part of this market. However, we are looking to work with entities to explore the possibilities. The Sandia technology is titled, ``Controlled Release of Molecular Components Comprising the Use of Fragmenting and Expanding Molecules.'' A non-disclosing description of the technology follows: A method of releasing molecules (guest molecules) from the matrix formed by the structure of another molecule (host molecule) in a controllable manner. Applications are in medicine, particularly in the treatment of cancer and viral infections. Similar effects can also be obtained by controlled fragmentation of a source molecule where molecular fragments form the active principle. Sandia can partner with both the private sector or other public sector institutions in a variety of business arrangements including CRADAs (Cooperative Research & Development Agreements), and commercial licenses, up to and including exclusive licenses within particular fields-of-use. Interested parties are asked to response by writing or faxing to: Joanne Trujullo, Technology Partnerships & Commercialization, Sandia National Laboratories, PO Box 5800- MS 1380, Albuquerque, NM 87185, FAX (505) 843-4175. Only parties that have the capacity to provide financial support for technology development, and/or the ability to bring the dendrimer technology to a product stage will be eligible to participate. Potential partners will be asked to fill out a participant data sheet and provide a brief commercialization plan for the technology. Please respond by April 12, 1996.

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