DHHS, National Institute on Drug Abuse, Contracts Management Branch, OPRM, Parklawn Building, Room 10-49, 5600 Fishers Lane, Rockville, Maryland 20857

A -- TOXICOLOGICAL SUPPORT FOR THE MEDICATIONS DEVELOPMENT PROGRAM SOL N01DA-6-8068 DUE 061096 POC Point of Contact, Kenneth E. Goodling, Contracting Officer, Phone: (301)443-6677 The National Institute on Drug Abuse is soliciting proposals from qualified organizations having in-house capacity to perform experiments in laboratory animals to systematically evaluate the pharmacological activities and toxicological effects of potential treatment drugs, both new and marketed, for treatment of drug abuse. Specifically, treatment drugs for two classes of drugs of abuse (cocaine and opiates) will be investigated preclinically. For the toxicological evaluation of new treatment drugs, toxicological properties and adverse interactions, including cardiovascular interactions, with drugs of abuse will be systematically tested. Offerors must submit with the proposal, documentation of a current DEA registration for Schedule II-V controlled substances and compliance with the NIH guidelines on the care and use of laboratory animals. It is estimated that a 4 year contract, with additional quantity options, will result from this procurement. Estimated issuance date of RFP No. N01DA-6-8068 is April 25, 1996 and responses are due to be received in the Contracting Office 45 calendar days thereafter. Written requests for copies of the solicitation will be honored if received within twenty calendar days after issuance of the solicitation. Written requests received after this period will be filled on a first-come, first-served basis until the supply is exhausted; however, there is no assurance that copies requested after the twentieth day will reach the requestor before the due date for receipt of responses. Written requests shall be forwarded to the attention of the Contracting Officer. (0096)

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