US Env. Protection Agency, CMD-RTP MD-33 (NCCM-KG), Research Triangle Park, NC 27711

B -- REPORTS OF PILOT STUDY RESULTS AND INTERIM FULL-SCALE STUDY RESULTS REGARDING HEALTH EFFECTS OF OUTDOOR AND INDOOR AIR HINESE CITIES. SOL 416025 POC Karen Z. Gibson, Contract Specialist (919)541-4556/Vickie Presnell, Contracting Officer. The U.S. Environmental Protection Agency has a requirement for reports of pilot study results and interim full-scale study results regarding health effects of outdoor and indoor air pollution in 4 Chinese cities. Annex 1 of the China-U.S. Environmental Protection Protocol specifies that the Chinese and U.S. sides shall conduct cooperative research on the respiratory health effects of Chinese urban air pollution in children and adults. The purpose of the research is to determine the health effects of exposure to indoor and outdoor air pollution in China, and to apply the findings to the risk assessment process in the U.S. and China. The research includes 4 cities, Chongqing, Guangzhou, Lanzhou, and Wuhan. Within each city, the research includes districts with relatively high and relatively low ambient air pollution levels (total 8 districts). Within each district the research also includes households with relatively high and relatively low indoor air pollution levels. Collected data include ambient air pollution measurements and standardized questionnaire information on indoor air pollution sources. Children's spirometric lung function is measured longitudinally and children's and adults' respiratory health status is determined by standardized questionnaire administered at intervals over the study period. Information on relevant covariates such as smoking, demographic characteristics, and socioeconomic status, is also gathered by standardized questionnaire. The contractor shall develop standardized code books, in English, suitable for encoding all data in both health questionnaire versions used in this research, all environmental exposure data collected, and annual average ambient particluate and sulfur oxide levels in each district from 1984 through 1995 within 6 weeks of after award. All variable names and codes shall be suitable for subsequent data entry onto computer using dBase III or dBase III Plus software. The contractor shall prepare standardized file structures, in English, for computer entry of all data mentioned above within 6 weeks after award. These file structures shall be entirely consistent with the standardized code books developed and shall be prepared using dBase III or dBase III Plus software. Using the standardized code books and file structures the contractor shall enter all environmental and health data from all data sources onto computer and copy each completed file onto a disk. The contractor shall prepare a report of pilot study findings in the 4 Chinese cities within 9 months after award. This report shall be prepared for submission to and publication in a peer-reviewed English language scientific journal. The contractor shall prepare a report of interim full-scale study findings in all study districts in the 4 Chinese cities within 11 months after award. This report shall be prepared for submission and subsequent publication in a peer-reviewed English-language scientific journal. This effort will require direct experience both with procedures and data formats employed by the Chinese side in this specific project, and with data formats used in China's nationwide municipal environmental data collection system. No telephonic requests will be honored. (0192)

Loren Data Corp. http://www.ld.com (SYN# 0006 19960711\B-0001.SOL)