National Cancer Institute, Research Contracts Branch, PSCS 6120 Executive Blvd, EPS/RM 638 Bethesda, MD 20892-7228

B -- BREAST CANCER CASE-CONTROL DIFFERENCES SOL RFQ60143(NR) POC Marsha Gorham, Purchasing Agent, (301)402-4509, Patricia Haun, Contracting Officer (301)402-4509. Under the authority of 41 U.S.C. 253(c)(1) Far 6.302-1, the National Cancer Institute intends to obtain services from Endocrine Sciences, 4301 Lost Hills Road, Calabasas Hills, California, 93101 to evaluate levels of endogenous estrogens. These services are associated with a NCI effort to assess breast cancer case-control differences in serum level of two estrogens: weekly bound estradiol plus estrone and estrone sultface. There is substantial interest in the possibility that higher levels of endogenous estrogens may increase the risk of breast cancer. Endocrine Sciences has demonstrated the ability to obtain the lowest coefficients of variations and the highest intraclass correlations at a very reasonable market price. This has been demonstrated by previous feasibilty studies to determine the reproducibility of results on the same day for large scale epidemiologic surveys. This notice of intent is not a solicitation for competitive proposals, however, if an interested party believes they can meet the above specifications, they must submit their capabilties, and furnish concise responses directed specifically to the requirement mentioned above. Information furnished shall include enough material to perform a proper evaluation. Offeror will not be notified of the evaluation results. AWARD WILL BE MADE 20 DAYS FROM THE RELEASE OF THIS SYNOPSIS. See Numbered Note(s): 1, 22. (0250)

Loren Data Corp. http://www.ld.com (SYN# 0022 19960909\B-0003.SOL)