National Institute on Drug Abuse/NIH, Contracts Management Branch, OPRM, 5600 Fishers Lane, PKLN BLDG, Room 10-49, Rockville, MD 20857

A -- IN VITRO BIOGENIC AMINE TRANSPORTER TESTING FOR POTENTIAL COCAINE TREATMENT MEDICATIONS SOL N01DA-7-8071 DUE 012197 POC Kenneth E. Goodling, Contracting Officer, Phone: (301) 443-6677, Fax: (301) 443-7595, EMail: kg25d@nih.gov The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having in-house capability to perform screening of in vitro transporter binding and uptake assays utilizing cells transfected with human dopamine, serotonin and norepinephrine transporters. Proprietary test compounds will be evaluated in established assays, and the resulting data will be utilized by the Cocaine Treatment Discovery Program of the NIDA Medications Development Division. Offerors must indica te possession of current DEA registration for Schedule II-V substances prior to award and have applied for Schedule I registration at the time of award. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of three years, with two options each for an additional year, as well as additional quantity options. RFP No. N01DA-7-8071 will be available electronically on or about December 4, 1996, and may be accessed through the NIH Gopher and/or the Internet by using the following electronic mail addresses and instruction: 1)NIH Home Page (via the World Wide Web): Access the NIH Home Page by using http://www.nih.gov . Once you are at the NIH Home Page, select ''Grants and Contracts''; select ''NIH Gopher directory: listed under the ''Contracts Page'' section. Once at the NIH R&D Gopher, select ''RFPs Available''; select ''NIDA''; and select ''RFP N01DA-7-8071''. 2)NIH Gopher: Point your Gopher client to GOPHER.NIH.GOV Port 70 (you should now be in the NIH Gopher). Select ''Grant and Research Information''; select ''R&D Request for Proposals (RFP)''; select ''RFPs Available''; select ''NIDA''; and, select ''RFP N01DA-7-8071''. Please note that the RFP for this acquisition will be streamlined to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualification, if any, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provid e additional documentation to the Contracting Officer. Response to this RFP will be due on January 21, 1997. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact:Kenneth E. Goodling, Contracting Officer Electronic Mail Address: kg25d@nih.gov Telephone: (301) 443-6677 Fax: (301) 443-7595(0320)

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