National Institute on Drug Abuse/NIH, Contracts Management Branch, OPRM, 5600 Fishers Lane, PKLN BLDG, Room 10-49, Rockville, MD 20857

A -- RECEPTOR ACTIVITY TESTING FOR MEDICATION DISCOVERY SOL N01DA-7-8072 DUE 022497 POC Kenneth E. Goodling, Contracting Officer, Phone: (301) 443-6677, Fax: (301) 443-7595, EMail: kg25d@nih.gov The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having in-house capability to perform in vitro receptor binding and functional activity assays. Proprietary test compounds will be evaluated in established assays, and the resulting data will be utilized by the Cocaine and Opiate Treatment Discovery Programs of the NIDA Medications Development Division. In addition, the successful offeror will work toward the development of new opioid receptor binding and functional activity assays. Offerors must indicate possession of current DEA registration for Schedule II-V substances prior to award and apply for Schedule I registration at the time of award. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of four years, with option quantities for additional evaluation of compounds and assay development. RFP No. N01DA-7-8072 will be available electronically on or about January 8, 1997, and may be accessed throug h the NIH Gopher and/or the Internet by using the following instructions: 1) NIH Home Page (via the World Wide Web): Access the NIH Home Page by using http://www.nih.gov . Once you are at the NIH Home Page, select "Grants and Contracts"; select "NIH Gopher directory: listed under the "Contracts Page" section. Once at the NIH R&D Gopher, select "RFPs Available"; select "NIDA"; and select "RFP N01DA-7-8072". (URL: gopher://gopher.nih.gov:70/11/res/rd-rfp) or, 2) NIH Gopher: Point your Gopher client to GO PHER.NIH.GOV Port 70 (you should now be in the NIH Gopher). Select "Grant and Research Information"; select "R&D Request for Proposals (RFP)"; select "RFPs Available"; select "NIDA"; and, select "RFP N01DA-7-8072". Please note that the RFP for this acquisition will be streamlined to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualifications, Technical Evaluation Criteria, and proposal preparation instructions. All information required for th e submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Response to this RFP will be due on February 24, 1997. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Kenneth E. Go odling, Contracting Officer, Electronic Mail Address: kg25d@nih.gov, Telephone: (301) 443-6677, Fax: (301) 443-7595 (0346)

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