National Cancer Institute, Research Contracts Branch, PCCS 6120 Executive Blvd, EPS/635, Bethesda, MD 20892-7226

A -- PLCO CANCER SCREENING TRIAL-SCREENING CENTER SPECIAL STUDIES SOL SEE BELOW POC Susan K. Hoffman, Contracting Officer, 301-496-8603. The National Cancer Institute (NCI), Division of Cancer Prevention and Control, Early Detection Branch intends to negotiate with the Maimonides Medical Center, NY, N01-CN-25523; Georgetown University Medical Center, DC, N01-CN-25522; Henry Ford Hospital, MI, N01-CN-25512; Straub Pacific Health Foundation, HI, N01-CN-25515; Marshfield Medical Research & Education Foundation, WI, N01-CN-25518; University of Colorado Health Sciences Center, CO, N01-CN-25514; University of Minnesota, MN, N01-CN-25513; University of Pittsburgh, PA, N01-CN-25511; University of Utah, UT, N01-CN-25524 and Washington University, MO, N01-CN-25516 for the inclusion of new work under the current contracts. These are the Screening Centers under contract with the NCI for performance of the Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial. Emerging issues which will affect NCIs ability to operationalize the findings of the PLCO Trial need to be investigated. These issues include but are not limited to quality of life, cost-effectiveness and test performance and other integral aspects of screening in large populations. Therefore, the statement of work has been modified to include performance of special studies which would determine quality of life, cost-effectiveness and test performance. Authority: 41 USC 253(c)(1), as set forth in FAR 6.302-1(a)1. No collect calls will be accepted See Numbered Note(s): 22. (0348)

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