National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, Executive Plaza South, Rm. 620, 6120 Executive Blvd., MSC 7224, Bethesda, MD 20892-7224

A -- INTERACTIVE EFFECTS OF GENETIC SUSCEPTIBILITY AND ENVIRONMENTAL FACTORS ON BREAST CANCER RISK: A POPULATION-BASED STUDY SOL N02-CP-71019-50 DUE 030397 POC Karen L. McFarlane, Contracting Officer Representative, (301) 496-8611 WEB: National Cancer Institute, http://cdbnet.access.gpo.gov. E-MAIL: National Cancer Institute, km63k@nih.gov. The National Cancer Institute is seeking qualified offerors to provide support for a study to assess the interactive effects of genetic and environmental effects on breast cancer risk. The offeror will work with the Government to interface with an ongoing extramurally supported case-control study which involves telephone interviews with over 10,000 subjects with newly diagnosed breast cancer and a comparable number of comparison subjects in three states (Wisconsin, Massachusetts, and New Hampshire). The current procurement will supplement the information collected in that study by focusing on approximately 2,000 women with a family history of breast cancer or ovarian cancer and a sample of 1,200 women without any such history. These women will be visited in their homes in order to collect additional interview information, take anthropometric measurements, and obtain biologic samples. The offeror must have experience in conducting similar epidemiologic studies in mutliple locales. The RFP N02-CP-71019-50 will be issued approximately 15 days after publication of this notice. Proposals will be due approximately 30 days after the issue date. Collect calls will not be accepted. (0013)

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