Contracts Management Branch, NICHD, National Institutes of Health, Executive Building, Suite 7A07, 6100 Executive Blvd MSC 7510, Bethesda, Maryland 20892-7510

A -- NEURODEVELOPMENTAL BATTERY FOR THE MATERNAL LIFESTYLE STUDY SOL SS-NICHD-CRMC-97-02 POC Contact Mr. Charles Newman, 301-496-4611/Contract Specialist E-MAIL: Charles Newman, newmanc@nih.gov. The National Institute of Child Health and Human Development (NICHD) has a continuing requirement for a maternal lifestyles study including the continued development of neurodevelopmental assessment batteries and data analysis. The "Neurodevelopmental Battery for the Maternal Lifestyles Study" project is a multi center longitudinal observational study of the sequelae of intrauterine polysubstance exposure on the outcome of infants and their families from birth to three years of age. The clinical portion of the project was initiated in 1991 at four Neonatal Research Network sites, Detroit, Miami, Memphis, and Providence. Under the current contract with E.P. Bradley Hospital (Brown University), scheduled to expire on 14 September 1997, a cohort of 1400 mother-infant dyads exposed to drugs and their controls, were followed and assessed from the age of one month through age three utilizing the battery developed by the contractor. Under the proposed new contract, study of the cohort will continue from age three through age seven. The contractor has developed plan for analysis of the data collected at the four centers and is currently implementing these analyses according to a design approved by the NICHD. In order to perform the continued work a new perspective contractor would need access a comparable cohort of mothers and infants, similar in age, that have been subject to a comparable neurodevelopmental assessment battery from infant to age three. A new contractor would be also be required to develop an NICHD approved assessment battery for infants from age three to seven years and an analysis plan by January 1998 for use during the 1988 annual examinations. As a result, the NICHD plans to award a five year contract to E.P. Bradley Hospital (Brown University) using other than full and open competition in accordance with 41 U.S.C. 252 C (1) and FAR 6.302-1. The purpose of this synopsis is to determine whether there are other sources capable of meeting the Government's requirements as described. Capability statements should be submitted within 45 days of publication of this synopsis to Mr. Charles Newman, NIH, NICHD, CMB, Executive Building, Room 7A07, 6100 Executive Boulevard, MSC 7510 Bethesda, Maryland 20892-7510 and should include details specifying how this work would be performed. See numbered Note 22. (0030)

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