U.S. Environmental Protection Agency, 26 W. Martin Luther King Dr., Cincinnati, OH 45268

A -- DEVELOPMENT OF TOXICOLOGICAL HEALTH/RISK ASSESSMENT PRODUCTS SOL PR-CI-97-10301 DUE 022597 POC Billy Oden -- 513-366-2126 WEB: Office of Acquisition Management -- Cincinnati Contracts Management Division, http://www.epa.gov/oam/cinn_cmd. E-MAIL: U.S. EPA -- Cincinnati Contracts Mangement Division, oden.billy@epamail.epa.gov. The Environmental Protection Agency is performing a "market search" for a contractor to provide support for 1) development of inhalation reference concentrations (RfCs), oral reference doses (RfDs), and cancer dose-response and/or unit risk assessments pertaining to long-term exposures as well as assessment of effects of acute exposures leading to derivation of acute reference exposure (ARE) values; and 2) research to improve and develop new dose-response assessment methodologies and to reduce uncertainty in existing methodologies. Chemicals for assessments will be selected by the U.S. EPA Project Officer. The data gathered in developing the RfCs, RfDs, AREs and cancer unit risk assessments as well as data gaps identified will serve as input into research support projects. Methodologies established by the U.S. EPA to develop RfCs, RfDs, AREs and cancer unit risk assessments will be utilized by the Contractor during the contract period. The Contractor shall be responsible for literature searches, compilation and evaluation of the toxicological literature to include data array, analysis, critique, synthesis and summary of relevant dose-response information. The Contractor shall provide the assessments in formats identified by the U.S. EPA Project Officer. The Contractor will draw upon the data generated in the assessment area to assist the U.S. EPA in identifying, developing and applying state-of-the-art methodologies to reduce areas of uncertainty in RfC, RfD, ARE and cancer unit risk assessments through statistical analyses and toxicological interpretations. EPA reserves the right to set this action aside for small businesses. The applicable SIC Code is 8999 with a size standard of $5 million in average annual receipts over the preceding three years. ALL INTERESTED SMALL BUSINESSES SHOULD FURNISH STATEMENTS REFERENCING THEIR CAPABILITIES WITHIN FIFTEEN (15) DAYS OF THIS NOTICE. It is anticipated that a cost plus fixed fee/level-of-effort contract will result from the award of this solicitation. The Government anticipates a level-of-effort of 5,590 direct labor hours per 12 months for the base contract year. The four option years (periods) are anticipated as follows: Option 1 -- 5,590 direct labor hours, Option Years 2, 3 and 4 -- 5,570 direct labor hours each for a total potential of 27,890 direct labor hours over 60 months. Small businesses are requested to submit appropriate documentation that demonstrates their capability to support this effort. This documentation should address as a minimum support for the requirement stated above. It is anticipated that this solicitation will be issued on or around mid-March 1997. This notice will be amended to indicate whether this action will be set-aside for small businesses or be processed under full and open competition. Interested parties may obtain a copy of the solicitation by submitting a written request. Telephone and facsimile requests will not be honored. Firms must identify their size status when requesting a copy of the solicitation. Firms who fail to do so shall be considered to be large businesses. A limited number of copies are available. Only one copy shall be issued to a corporate entity, regardless of requests from one or more different geographical locations. A copy of the preliminary source list will be issued to all prospective offerors along with the solicitation. A separate request is not necessary. All responsible sources may submit a proposal which will be considered by the Agency. The Government does not intend to acquire a commercial item using Part 12.***** (0044)

Loren Data Corp. http://www.ld.com (SYN# 0021 19970218\A-0021.SOL)