National Institute of Allergy and Infectious Diseases, Contract Management Branch, Solar Building, Room 3C07, 6003 Executive Boulevard MSC 7610, Bethesda, MD 20892-7610

A -- PRIMARY IMMUNODEFICIENCY DISEASE REGISTRY SOL RFP-NIH-NIAID-DAIT-97-11 DUE 052097 POC Judith Rubinstein, Contract Specialist, (301) 496-2509, Rosemary McCabe Hamill, Contracting Officer, (301) 496-0384 The Clinical Immunology Branch, Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases has a requirement for the acquisition of a registry for U.S. residents affected by several primary immunodeficiency diseases. The work will require expertise and knowledge of these diseases (including the complex clinical manifestations and the socioeconomic impact on affected families); interactions with individuals affected by these diseases, their physicians, and researchers in primary immunodeficiency diseases; and expertise and knowledge of all aspects of the operation of a registry. The diseases are: Severe Combined Immunodeficiency Disease (SCID), X-linked Agammaglobulinemia (XLA), Wiskott-Aldrich Syndrome (WAS), Common Variable Immunodeficiency (CVID), Chronic Granulomatous Disease (CGD), DiGeorge Anomaly, Leukocyte Adhesion Deficiency (LAD), and Hyper IgM Syndrome. The contract will have two components, A and B. The registry for SCID, XLA, WAS, CVID and CGD will comprise Part A, for which a single, completion type contract will be awarded. Part B describes activities for the Government to support at its option, which may include expansion of the registry to include any one, two, or all three of the diseases DiGeorge Anomaly, LAD, and Hyper IgM syndrome. It is anticipated that one cost-reimbursement, completion contract will be awarded for a period of five (5) years. RFP NIAID-DAIT-97-11 will be available electronically on or about March 18, 1997 and may be accessed through the NIH Home Page or the NIH Gopher by using the following electronic mail addresses and instructions: NIH Home Page (via the World Wide Web): Access the NIH Home Page by using http://www.nih.gov . Once you are at the NIH Home Page, select AGrants & Contracts@, then under the "Contracts" page heading, select "Funding Opportunities" to access the AR&D Requests for Proposals (RFP)" in the gopher directory. Once in the gopher directory, select "RFP's Available"; "NIAID"; and finally, "RFP NIH-NIAID-DAIT-97-11." This RFP is only available via the NIH Home Page. Instructions for this acquisition and for proper submission are set forth at the Web Site mentioned above. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on or about May 20, 1997. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. (0058)

Loren Data Corp. http://www.ld.com (SYN# 0005 19970303\A-0005.SOL)